Drug General Information
Drug ID
D0F1ZI
Former ID
DIB007655
Drug Name
F-16-IL-2 fusion protein
Synonyms
Teleukin; F-16-IL-2; F-16-IL-2 fusion protein (cancer); F-16-IL-2 fusion protein (cancer), Philogen
Indication Solid tumours [ICD9: 140-199, 210-229; ICD10:C00-D48] Phase 2 [549056]
Company
Philogen SpA
Target and Pathway
Target(s) Tenascin Target Info Modulator [550459]
KEGG Pathway PI3K-Akt signaling pathway
Focal adhesion
ECM-receptor interaction
MicroRNAs in cancer
NetPath Pathway IL4 Signaling Pathway
TGF_beta_Receptor Signaling Pathway
Pathway Interaction Database Beta1 integrin cell surface interactions
Beta3 integrin cell surface interactions
Alpha9 beta1 integrin signaling events
Syndecan-4-mediated signaling events
Reactome Integrin cell surface interactions
Syndecan interactions
ECM proteoglycans
WikiPathways TGF beta Signaling Pathway
Focal Adhesion
Syndecan interactions
Extracellular matrix organization
Integrin cell surface interactions
References
Ref 549056Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800031837)
Ref 550459National Cancer Institute Drug Dictionary (drug id 674718).

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