Drug Information

Drug General Information
Drug ID
D0F2IC
Former ID
DIB015245
Drug Name
NTx-488
Synonyms
Prolactin-containing multiple sclerosis therapy, Stem Cell Therapeutics
Indication Multiple scierosis [ICD9: 340; ICD10:G35] Discontinued in Phase 2 [548752]
Company
Stem Cell Therapeutics Corp
Target and Pathway
Target(s) Prolactin Target Info Modulator [548751]
KEGG Pathway Cytokine-cytokine receptor interaction
Neuroactive ligand-receptor interaction
PI3K-Akt signaling pathway
Jak-STAT signaling pathway
Prolactin signaling pathway
NetPath Pathway IL2 Signaling Pathway
Pathway Interaction Database ErbB4 signaling events
Signaling events mediated by PTP1B
Glucocorticoid receptor regulatory network
Validated nuclear estrogen receptor alpha network
Reactome Prolactin receptor signaling
Amyloid formation
Growth hormone receptor signaling
WikiPathways Prostaglandin Synthesis and Regulation
EV release from cardiac cells and their functional effects
Prolactin receptor signaling
Growth hormone receptor signaling
JAK/STAT
References
Ref 548752Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800028330)
Ref 548751Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800028330)

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