Drug Information

Drug General Information
Drug ID
D0G1IG
Former ID
DIB002978
Drug Name
F-16-131I
Synonyms
Tenarad; F-16-131I; Radiolabeled scFv antibody F-16 (solid tumor/hematological malignancy), Philogen
Drug Type
Antibody
Indication Hematological malignancies [ICD9: 200-209; ICD10:C81-C86] Phase 1/2 [549057]
Company
Philogen SpA
Target and Pathway
Target(s) Tenascin Target Info [551822]
KEGG Pathway PI3K-Akt signaling pathway
Focal adhesion
ECM-receptor interaction
MicroRNAs in cancer
NetPath Pathway IL4 Signaling Pathway
TGF_beta_Receptor Signaling Pathway
Pathway Interaction Database Beta1 integrin cell surface interactions
Beta3 integrin cell surface interactions
Alpha9 beta1 integrin signaling events
Syndecan-4-mediated signaling events
Reactome Integrin cell surface interactions
Syndecan interactions
ECM proteoglycans
WikiPathways TGF beta Signaling Pathway
Focal Adhesion
Syndecan interactions
Extracellular matrix organization
Integrin cell surface interactions
References
Ref 549057Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800031840)
Ref 551822Tumor-Associated Fibroblasts and their Matrix. Springer. Margareta M. Mueller,Norbert E. Fusenig, 2011. Page(775).

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