Drug Information

Drug General Information
Drug ID
D0H7RV
Former ID
DIB018410
Drug Name
[3H]SB-733993
Synonyms
[3H]-(2R)-3-[(2R,6S)-2,6-dimethylpiperidin-1-yl]-2-hydroxy-S-(naphthalen-1-yl)propane-1-sulfonamido ; [3H]-SB-733993
Drug Type
Small molecular drug
Indication Discovery agent Investigative [467732]
Structure
Download
2D MOL
Formula
C20H28N2O3S
InChI
InChI=1S/C20H28N2O3S/c1-15-7-5-8-16(2)22(15)14-18(23)13-21-26(24,25)20-12-6-10-17-9-3-4-11-19(17)20/h3-4,6,9-12,15-16,18,21,23H,5,7-8,13-14H2,1-2H3/t15-,16+,18-/m1/s1/i10T
InChIKey
GJXFPIGLCXZHTN-LDHSEPLKSA-N
PubChem Compound ID
73755092
PubChem Substance ID
178101219
Target and Pathway
Target(s) Sodium- and chloride-dependent glycine transporter 1 Target Info Modulator [531091]
Reactome Na+/Cl- dependent neurotransmitter transporters
WikiPathways NRF2 pathway
References
Ref 467732(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4491).
Ref 531091Pharmacological characterisation of the GlyT-1 glycine transporter using two novel radioligands. Neuropharmacology. 2010 Nov;59(6):558-65.

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