Drug Information

Drug General Information
Drug ID
D0I5ZO
Former ID
DIB016855
Drug Name
AS-1522489-00
Synonyms
AS-1522489-00; GlyT-1 inhibitors (schizophrenia, dementia); GlyT-1 inhibitors (schizophrenia, dementia), Astellas
Indication Dementia [ICD9: 290-294; ICD10:F01-F07] Investigative [543979]
Company
Astellas Pharma Inc
Target and Pathway
Target(s) Sodium- and chloride-dependent glycine transporter 1 Target Info Inhibitor [543979]
Reactome Na+/Cl- dependent neurotransmitter transporters
WikiPathways NRF2 pathway
References
Ref 543979(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 935).
Ref 543979(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 935).

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