Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0K2CV
|
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| Former ID |
DNC012137
|
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| Drug Name |
HOE-694
|
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| Drug Type |
Small molecular drug
|
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| Indication | Heart arrhythmia [ICD10:I47-I49] | Terminated | [534245] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C14H20N4O3S
|
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| Canonical SMILES |
CS(=O)(=O)C1=C(C=CC(=C1)C(=O)N=C(N)N)N2CCCCC2.Cl
|
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| InChI |
1S/C14H20N4O3S.ClH/c1-22(20,21)12-9-10(13(19)17-14(15)16)5-6-11(12)18-7-3-2-4-8-18;/h5-6,9H,2-4,7-8H2,1H3,(H4,15,16,17,19);1H
|
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| InChIKey |
XARNMUQDYQFLNA-UHFFFAOYSA-N
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Sodium/hydrogen exchanger 1 | Target Info | Inhibitor | [534413] | |
| Sodium/hydrogen exchanger 3 | Target Info | Inhibitor | [534413] | ||
| KEGG Pathway | cAMP signaling pathway | ||||
| Cardiac muscle contraction | |||||
| Adrenergic signaling in cardiomyocytes | |||||
| Regulation of actin cytoskeleton | |||||
| Thyroid hormone signaling pathway | |||||
| Salivary secretion | |||||
| Gastric acid secretion | |||||
| Pancreatic secretion | |||||
| Bile secretion | |||||
| Proteoglycans in cancerhsa04964:Proximal tubule bicarbonate reclamation | |||||
| Protein digestion and absorption | |||||
| Mineral absorption | |||||
| Reactome | Hyaluronan uptake and degradation | ||||
| References | |||||
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