Drug General Information
Drug ID	D0K6LA
Former ID	DIB000401
Drug Name	OPC-22575
Synonyms	OPC-22321; OPC-22381
Indication	Ulcerative colitis [ICD9: 556; ICD10:K51]		Investigative	[543965]
Company	Otsuka Pharmaceutical Co Ltd
Structure		Download 2D MOL 3D MOL
Canonical SMILES	c1(nc2c([nH]1)cc(c(c2)F)OC)S(=O)Cc1c2c(C(CCN2CC)N(CC=C)<br />C)ccc1
CAS Number	CAS 112645-53-1
Target and Pathway
Target(s)	Potassium-transporting ATPase alpha chain 1	Target Info	Modulator	[543965]
KEGG Pathway	Oxidative phosphorylation
	Collecting duct acid secretion
	Gastric acid secretion
PathWhiz Pathway	Gastric Acid Production
Reactome	Ion transport by P-type ATPases
WikiPathways	Iron uptake and transport
	Secretion of Hydrochloric Acid in Parietal Cells
References
Ref 543965	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 849).
Ref 543965	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 849).

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