Drug Information

Drug General Information
Drug ID
D0KP9A
Former ID
DNCL002306
Drug Name
Anti-PD-L1
Synonyms
BMS-936559
Drug Type
Antibody
Indication HIV-1 infection; Solid tumours [ICD9: 001-139, 042, 140-199, 210-229; ICD10:B20-B24, C00-D48] Phase 1 [523665]
Company
Bristol-Myers Squibb
Target and Pathway
Target(s) Programmed cell deathe?Y? ligand 1 (PD-L1) Target Info [531933]
KEGG Pathway Cell adhesion molecules (CAMs)
Reactome PD-1 signaling
WikiPathways Costimulation by the CD28 family
References
Ref 523665ClinicalTrials.gov (NCT01455103) Phase 1 Biomarker Study of Anti-PDL-1 in Advanced Melanoma. U.S. National Institutes of Health.
Ref 531933Safety and activity of anti-PD-L1 antibody in patients with advanced cancer. N Engl J Med. 2012 Jun 28;366(26):2455-65.

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