Drug General Information
Drug ID	D0L7AO
Former ID	DNC014875
Drug Name	Gababutin
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[530504]
Structure		Download 2D MOL 3D MOL
Formula	C8H15NO2
Canonical SMILES	C1CCC(C1)(CC(=O)O)CN
InChI	1S/C8H15NO2/c9-6-8(5-7(10)11)3-1-2-4-8/h1-6,9H2,(H,10,11)
InChIKey	MKGSCDBHUPQQMX-UHFFFAOYSA-N
PubChem Compound ID	9898895
Target and Pathway
Target(s)	Voltage-dependent calcium channel subunit alpha-2/delta-1	Target Info	Inhibitor	[530504]
KEGG Pathway	MAPK signaling pathway
	Cardiac muscle contraction
	Adrenergic signaling in cardiomyocytes
	Oxytocin signaling pathway
	Hypertrophic cardiomyopathy (HCM)
	Arrhythmogenic right ventricular cardiomyopathy (ARVC)
	Dilated cardiomyopathy
PANTHER Pathway	Muscarinic acetylcholine receptor 2 and 4 signaling pathway
WikiPathways	Arrhythmogenic Right Ventricular Cardiomyopathy
	miR-targeted genes in muscle cell - TarBase
	miR-targeted genes in lymphocytes - TarBase
References
Ref 530504	Bioorg Med Chem Lett. 2010 Jan 1;20(1):362-5. Epub 2009 Oct 25.Synthesis and in vivo evaluation of 3-substituted gababutins.
Ref 530504	Bioorg Med Chem Lett. 2010 Jan 1;20(1):362-5. Epub 2009 Oct 25.Synthesis and in vivo evaluation of 3-substituted gababutins.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.