Drug Information

Drug General Information
Drug ID
D0L8EO
Former ID
DIB010079
Drug Name
Anti-TLR3 mabs
Synonyms
Anti-TLR3 mAbs (autoimmune and inflammatory disorders)
Drug Type
Monoclonal antibody
Indication Autoimmune diabetes [ICD10:E08-E13] Investigative [543473]
Company
Innate Pharma SA
Target and Pathway
Target(s) Toll-like receptor 3 Target Info Modulator [543473]
KEGG Pathway Toll-like receptor signaling pathway
Hepatitis C
Hepatitis B
Influenza A
Herpes simplex infection
NetPath Pathway TCR Signaling Pathway
PANTHER Pathway Toll receptor signaling pathway
Pathway Interaction Database Endogenous TLR signaling
Reactome Ligand-dependent caspase activation
MyD88-independent TLR3/TLR4 cascade
Trafficking and processing of endosomal TLR
RIP-mediated NFkB activation via ZBP1
TRIF-mediated programmed cell death
Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
IKK complex recruitment mediated by RIP1
TRAF6 mediated induction of TAK1 complex
WikiPathways Toll-like receptor signaling pathway
Cytosolic sensors of pathogen-associated DNA
Toll-Like Receptors Cascades
MyD88-independent cascade
Trafficking and processing of endosomal TLR
Regulation of toll-like receptor signaling pathway
References
Ref 543473(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1753).
Ref 543473(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1753).

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.