Drug Information

Drug General Information
Drug ID
D0NC1Q
Former ID
DNCL002106
Drug Name
AMG 172
Indication Renal cancer [ICD9: 140-229, 189; ICD10:C64] Phase 1 [523744]
Company
Amgen
Target and Pathway
Target(s) CD70 Target Info Modulator [550482]
KEGG Pathway Cytokine-cytokine receptor interaction
NetPath Pathway IL2 Signaling Pathway
TNFalpha Signaling Pathway
RANKL Signaling Pathway
Reactome TNFs bind their physiological receptors
References
Ref 523744ClinicalTrials.gov (NCT01497821) AMG 172 First in Human Study in Patients With Kidney Cancer. U.S. National Institutes of Health.
Ref 550482National Cancer Institute Drug Dictionary (drug id 721679).

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