Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0O3QW
|
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| Former ID |
DIB002575
|
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| Drug Name |
Trodusquemine
|
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| Synonyms |
Produlestan; Trodulamine; Aminosterol 1436; MSI-1436; Aminosterols (obesity, type 2 diabetes), Genaera
|
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| Drug Type |
Small molecular drug
|
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| Indication | Obesity [ICD9: 278; ICD10:E66] | Phase 1 | [522516] | ||
| Company |
Genaera
|
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| Structure |
|
Download2D MOL |
|||
| Formula |
C37H72N4O5S
|
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| Canonical SMILES |
[C@@]12([C@H]([C@H]3[C@@H]([C@@]4([C@@H](C[C@H]3O)C[C@H<br />](CC4)NCCCNCCCCNCCCN)C)CC2)CC[C@@H]1[C@@H](CC[C@@H](OS(<br />=O)(=O)O)C(C)C)C)C
|
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| CAS Number |
CAS 186139-09-3
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Protein tyrosine phosphatase-1B | Target Info | Inhibitor | [530636] | |
| KEGG Pathway | Adherens junction | ||||
| Insulin signaling pathway | |||||
| NetPath Pathway | FSH Signaling Pathway | ||||
| PANTHER Pathway | Cadherin signaling pathway | ||||
| Pathway Interaction Database | Insulin Pathway | ||||
| Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) | |||||
| Signaling events mediated by PTP1B | |||||
| Calcineurin-regulated NFAT-dependent transcription in lymphocytes | |||||
| Signaling events mediated by TCPTP | |||||
| IGF1 pathway | |||||
| EGF receptor (ErbB1) signaling pathway | |||||
| Posttranslational regulation of adherens junction stability and dissassembly | |||||
| PDGFR-beta signaling pathway | |||||
| N-cadherin signaling events | |||||
| References | |||||
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