Drug Information

Drug General Information
Drug ID
D0OZ4J
Former ID
DIB004554
Drug Name
RG-7446
Drug Type
Antibody
Indication Urothelial carcinoma [ICD10:C00-D49] Approved [889440]
Bladder cancer [ICD9: 188; ICD10:C67] Phase 3 [549279]
Company
Genentech
Target and Pathway
Target(s) Programmed cell deathe?Y? ligand 1 (PD-L1) Target Info [544363]
KEGG Pathway Cell adhesion molecules (CAMs)
Reactome PD-1 signaling
WikiPathways Costimulation by the CD28 family
References
Ref 549279Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800034572)
Ref 8894402016 FDA drug approvals. Nat Rev Drug Discov. 2017 Feb 2;16(2):73-76. doi: 10.1038/nrd.2017.14.
Ref 544363PD-1 as a potential target in cancer therapy. Cancer Med. 2013 October; 2(5): 662-673.

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