Drug General Information
Drug ID
D0P3SH
Former ID
DIB004851
Drug Name
ReN-1826
Synonyms
Neurotrophin receptor program, Enact; Neurotrophin receptor program, ReNeuron
Indication Central nervous system disease [ICD10:G00-G99] Terminated [547600]
Company
University of Bristol
Target and Pathway
Target(s) Neurotrophin-4 ligand Target Info Inhibitor [528418]
Neurotrophin-3 Target Info Inhibitor [528418]
KEGG Pathway MAPK signaling pathway
Neurotrophin signaling pathwayhsa04010:MAPK signaling pathway
Neurotrophin signaling pathway
NetPath Pathway TNFalpha Signaling Pathway
Pathway Interaction Database SHP2 signaling
p75(NTR)-mediated signaling
Neurotrophic factor-mediated Trk receptor signalingshp2_pathway:SHP2 signaling
Neurotrophic factor-mediated Trk receptor signaling
Trk receptor signaling mediated by the MAPK pathway
WikiPathways MAPK Signaling Pathway
Differentiation PathwayWP2380:BDNF signaling pathway
Integrated Pancreatic Cancer Pathway
References
Ref 547600Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800017722)
Ref 528418Pulmonary distribution, regulation, and functional role of Trk receptors in a murine model of asthma. J Allergy Clin Immunol. 2006 Sep;118(3):597-605. Epub 2006 Jul 3.

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