Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0QK2E
|
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| Former ID |
DNC005792
|
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| Drug Name |
SCH-205831
|
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| Drug Type |
Small molecular drug
|
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| Indication | Thrombosis [ICD9: 437.6, 453, 671.5, 671.9; ICD10:I80-I82] | Investigative | [528902] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C27H28F3NO2
|
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| Canonical SMILES |
CC1C2C(CC3CCCCC3C2C=CC4=NC=C(C=C4)C5=CC(=CC=C5)C(F)(F)F<br />)C(=O)O1
|
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| InChI |
1S/C27H28F3NO2/c1-16-25-23(22-8-3-2-5-18(22)14-24(25)26(32)33-16)12-11-21-10-9-19(15-31-21)17-6-4-7-20(13-17)27(28,29)30/h4,6-7,9-13,15-16,18,22-25H,2-3,5,8,14H2,1H3/b12-11+/t16-,18+,22-,23+,24-,25+/m1/s1
|
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| InChIKey |
PQLBJVPZXNPVOS-HLBWOJLBSA-N
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Thrombin receptor | Target Info | Inhibitor | [528902] | |
| NetPath Pathway | TGF_beta_Receptor Signaling Pathway | ||||
| TCR Signaling Pathway | |||||
| PANTHER Pathway | Angiogenesis | ||||
| Blood coagulation | |||||
| Pathway Interaction Database | PAR1-mediated thrombin signaling events | ||||
| WikiPathways | Complement and Coagulation Cascades | ||||
| Regulation of Actin Cytoskeleton | |||||
| GPCRs, Class A Rhodopsin-like | |||||
| IL1 and megakaryotyces in obesity | |||||
| Apoptosis-related network due to altered Notch3 in ovarian cancer | |||||
| Hematopoietic Stem Cell Differentiation | |||||
| Gastrin-CREB signalling pathway via PKC and MAPK | |||||
| Thrombin signalling through proteinase activated receptors (PARs) | |||||
| GPCR ligand binding | |||||
| GPCR downstream signaling | |||||
| GPCRs, Other | |||||
| References | |||||
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