Drug Information

Drug General Information
Drug ID
D0T6DR
Former ID
DNC011948
Drug Name
3-Aminomethyl-5-methyl-hexanoic acid
Drug Type
Small molecular drug
Indication Discovery agent Investigative [551273]
Structure
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2D MOL

3D MOL
Formula
C8H17NO2
Canonical SMILES
CCC(CC(C)C)NC
InChI
1S/C8H19N/c1-5-8(9-4)6-7(2)3/h7-9H,5-6H2,1-4H3
InChIKey
WXRNKMCXPUWCHR-UHFFFAOYSA-N
PubChem Compound ID
4715169
Target and Pathway
Target(s) Voltage-dependent calcium channel subunit alpha-2/delta-2 Target Info Inhibitor [551273]
Voltage-dependent calcium channel subunit alpha-2/delta-1 Target Info Inhibitor [551273]
Voltage-dependent calcium channel subunit alpha-2/delta-3 Target Info Inhibitor [551273]
KEGG Pathway MAPK signaling pathway
Cardiac muscle contraction
Adrenergic signaling in cardiomyocytes
Oxytocin signaling pathway
Hypertrophic cardiomyopathy (HCM)
Arrhythmogenic right ventricular cardiomyopathy (ARVC)
Dilated cardiomyopathyhsa04010:MAPK signaling pathway
Dilated cardiomyopathy
PANTHER Pathway Muscarinic acetylcholine receptor 2 and 4 signaling pathway
PathWhiz Pathway Muscle/Heart Contraction
Pancreas Function
Reactome Depolarization of the Presynaptic Terminal Triggers the Opening of Calcium Channels
Adrenaline,noradrenaline inhibits insulin secretion
Regulation of insulin secretionR-HSA-112308:Depolarization of the Presynaptic Terminal Triggers the Opening of Calcium Channels
WikiPathways Arrhythmogenic Right Ventricular Cardiomyopathy
Integration of energy metabolismWP2118:Arrhythmogenic Right Ventricular Cardiomyopathy
miR-targeted genes in muscle cell - TarBase
miR-targeted genes in lymphocytes - TarBaseWP2118:Arrhythmogenic Right Ventricular Cardiomyopathy
References
Ref 551273Enantioselective synthesis of PD144723: a potent stereospecific anticonvulsant, Bioorg. Med. Chem. Lett. 4(6):823-826 (1994).
Ref 551273Enantioselective synthesis of PD144723: a potent stereospecific anticonvulsant, Bioorg. Med. Chem. Lett. 4(6):823-826 (1994).

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