Drug Information

Drug General Information
Drug ID
D0U1CN
Former ID
DIB020272
Drug Name
LY2365109
Synonyms
LY-2365109; LY 2365109
Drug Type
Small molecular drug
Indication Discovery agent Investigative [467953]
Structure
Download
2D MOL
Formula
C22H27NO5
InChI
InChI=1S/C22H27NO5/c1-22(2,3)17-11-15(16-6-8-19-20(12-16)28-14-27-19)5-7-18(17)26-10-9-23(4)13-21(24)25/h5-8,11-12H,9-10,13-14H2,1-4H3,(H,24,25)
InChIKey
FKPLJWGRBCQLTL-UHFFFAOYSA-N
PubChem Compound ID
11552757
PubChem Substance ID
16654993, 23674100, 42694653, 77432753, 124961484, 178101423, 232064567
Target and Pathway
Target(s) Sodium- and chloride-dependent glycine transporter 1 Target Info Inhibitor [543979]
Reactome Na+/Cl- dependent neurotransmitter transporters
WikiPathways NRF2 pathway
References
Ref 467953(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4712).
Ref 543979(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 935).

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