Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0U6BB
|
||||
| Former ID |
DNC004275
|
||||
| Drug Name |
L-703014
|
||||
| Drug Type |
Small molecular drug
|
||||
| Indication | Thromboembolism [ICD9: 437.6, 453, 671.5, 671.9; ICD10:I80-I82] | Terminated | [545810] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C23H32N4O4
|
||||
| Canonical SMILES |
C1CNCCC1CCCC(=O)NCC(=O)NC(CCC2=CNC3=CC=CC=C32)C(=O)O
|
||||
| InChI |
1S/C23H32N4O4/c28-21(7-3-4-16-10-12-24-13-11-16)26-15-22(29)27-20(23(30)31)9-8-17-14-25-19-6-2-1-5-18(17)19/h1-2,5-6,14,16,20,24-25H,3-4,7-13,15H2,(H,26,28)(H,27,29)(H,30,31)/t20-/m1/s1
|
||||
| InChIKey |
WDRKDCBKBCRZSK-HXUWFJFHSA-N
|
||||
| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Glycoprotein IIb/IIIa receptor | Target Info | Modulator | ||
| Reactome | Platelet degranulation | ||||
| Elastic fibre formation | |||||
| PECAM1 interactions | |||||
| Molecules associated with elastic fibres | |||||
| Integrin cell surface interactions | |||||
| Syndecan interactions | |||||
| ECM proteoglycans | |||||
| Integrin alphaIIb beta3 signaling | |||||
| GRB2:SOS provides linkage to MAPK signaling for Integrins | |||||
| p130Cas linkage to MAPK signaling for integrins | |||||
| VEGFA-VEGFR2 Pathway | |||||
| MAP2K and MAPK activation | |||||
| References | |||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.