Drug Information
Drug General Information | |||||
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Drug ID |
D0UZ4G
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Former ID |
DIB006435
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Drug Name |
99mTc-rBitistatin
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Indication | Embolism [ICD10:I74, I82] | Phase 1/2 | [522520] | ||
Company |
Temple University
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Target and Pathway | |||||
Target(s) | Glycoprotein IIb/IIIa receptor | Target Info | Modulator | [529086] | |
Reactome | Platelet degranulation | ||||
Elastic fibre formation | |||||
PECAM1 interactions | |||||
Molecules associated with elastic fibres | |||||
Integrin cell surface interactions | |||||
Syndecan interactions | |||||
ECM proteoglycans | |||||
Integrin alphaIIb beta3 signaling | |||||
GRB2:SOS provides linkage to MAPK signaling for Integrins | |||||
p130Cas linkage to MAPK signaling for integrins | |||||
VEGFA-VEGFR2 Pathway | |||||
MAP2K and MAPK activation | |||||
References |
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