Drug Information
Drug General Information | |||||
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Drug ID |
D0V3HC
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Former ID |
DIB005948
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Drug Name |
Anti-CD40-XTEN
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Synonyms |
CD40 ligand receptor antagonist (XTEN, rheumatoid arthritis/transplant rejection), Amunix
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Indication | Rheumatoid arthritis [ICD9: 710-719, 714; ICD10:M05-M06] | Investigative | [543514] | ||
Company |
Amunix Inc
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Target and Pathway | |||||
Target(s) | Tumor necrosisfactor receptor superfamily member 5 | Target Info | Antagonist | [543514] | |
KEGG Pathway | Cytokine-cytokine receptor interaction | ||||
NF-kappa B signaling pathway | |||||
Cell adhesion molecules (CAMs) | |||||
Toll-like receptor signaling pathway | |||||
Intestinal immune network for IgA production | |||||
Malaria | |||||
Toxoplasmosis | |||||
HTLV-I infection | |||||
Epstein-Barr virus infection | |||||
Transcriptional misregulation in cancer | |||||
Asthma | |||||
Autoimmune thyroid disease | |||||
Systemic lupus erythematosus | |||||
Allograft rejection | |||||
Primary immunodeficiency | |||||
Viral myocarditis | |||||
Pathway Interaction Database | CD40/CD40L signaling | ||||
References |
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