Drug Information

Drug General Information
Drug ID
D0V3ZN
Former ID
DIB016148
Drug Name
AG-SPT201
Synonyms
SPT201; S-pantoprazole sodium trihydrate (ulcer), Ahn-Gook; (S)-pantoprazole sodium trihydrate
Indication Ulcerative colitis [ICD9: 556; ICD10:K51] Phase 3 [523556]
Company
Ahn-Gook Pharmaceuticals Co Ltd
Structure
Download
2D MOL

3D MOL
Canonical SMILES
c1(nc2c([n-]1)ccc(c2)OC(F)F)[S@@](=O)Cc1c(c(ccn1)OC)OC.<br />[Na+].O.O.O
CAS Number
CAS 142678-35-1
Target and Pathway
Target(s) Potassium-transporting ATPase alpha chain 1 Target Info Modulator [525464]
KEGG Pathway Oxidative phosphorylation
Collecting duct acid secretion
Gastric acid secretion
PathWhiz Pathway Gastric Acid Production
Reactome Ion transport by P-type ATPases
WikiPathways Iron uptake and transport
Secretion of Hydrochloric Acid in Parietal Cells
References
Ref 523556ClinicalTrials.gov (NCT01400945) Efficacy Study of AGSPT201 Tablet to Treat Gastroesophageal Reflux Disease. U.S. National Institutes of Health.
Ref 525464Effects of pantoprazole, a novel H+/K+-ATPase inhibitor, on duodenal ulcerogenic and healing responses in rats: a comparative study with omeprazole and lansoprazole. J Gastroenterol Hepatol. 1999 Mar;14(3):251-7.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.