Drug General Information
Drug ID	D0W1DI
Former ID	DIB015316
Drug Name	AS-1670542
Drug Type	Small molecular drug
Indication	Thrombocytopenic purpura [ICD10:D69]		Investigative	[543468]
Company	Astellas Pharma Inc
Structure		Download 2D MOL 3D MOL
Formula	C29H34Cl2N6O3S2
Canonical SMILES	c1c(cc(c(n1)N1CCC(CC1)C(=O)O)Cl)C(=O)Nc1sc(c(n1)c1scc(c<br />1)Cl)CN(C)C1CCC1
PubChem Compound ID	9852519
Target and Pathway
Target(s)	Thrombopoietin Receptor	Target Info	Agonist	[543468]
KEGG Pathway	Cytokine-cytokine receptor interaction
	Jak-STAT signaling pathway
WikiPathways	Platelet Aggregation (Plug Formation)
References
Ref 543468	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1722).
Ref 543468	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1722).

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