Drug Information

Drug General Information
Drug ID
D0W7IL
Former ID
DCL000247
Drug Name
Thrombopoietin
Indication Thrombocytopenia [ICD9: 287.3, 287.4, 287.5; ICD10:D69.6, P61.0] Discontinued in Phase 3 [468146], [547808]
Company
Genentech
Target and Pathway
Target(s) Thrombopoietin Receptor Target Info Agonist [535128]
KEGG Pathway Cytokine-cytokine receptor interaction
Jak-STAT signaling pathway
WikiPathways Platelet Aggregation (Plug Formation)
References
Ref 468146(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5063).
Ref 547808Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800019480)
Ref 535128Technology evaluation: thrombopoietin, Genentech/Pharmacia & Upjohn. Curr Opin Mol Ther. 2000 Apr;2(2):211-5.

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