Drug General Information
Drug ID	D0X5RA
Former ID	DNC005614
Drug Name	6-amino-5-bromouracil
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[529048]
Structure		Download 2D MOL 3D MOL
Formula	C4H4BrN3O2
Canonical SMILES	C1(=C(NC(=O)NC1=O)N)Br
InChI	1S/C4H4BrN3O2/c5-1-2(6)7-4(10)8-3(1)9/h(H4,6,7,8,9,10)
InChIKey	FSLBEEVCUZFKRL-UHFFFAOYSA-N
PubChem Compound ID	80578
Target and Pathway
Target(s)	Thymidine phosphorylase	Target Info	Inhibitor	[529048]
BioCyc Pathway	Pyrimidine deoxyribonucleosides degradation
KEGG Pathway	Pyrimidine metabolism
	Drug metabolism - other enzymes
	Metabolic pathways
	Bladder cancer
NetPath Pathway	TSH Signaling Pathway
PathWhiz Pathway	Pyrimidine Metabolism
WikiPathways	Bladder Cancer
	Metabolism of nucleotides
	Fluoropyrimidine Activity
References
Ref 529048	Eur J Med Chem. 2008 Jun;43(6):1248-60. Epub 2007 Aug 6.Xanthine oxidase-activated prodrugs of thymidine phosphorylase inhibitors.
Ref 529048	Eur J Med Chem. 2008 Jun;43(6):1248-60. Epub 2007 Aug 6.Xanthine oxidase-activated prodrugs of thymidine phosphorylase inhibitors.

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