Drug Information

Drug General Information
Drug ID
D0XY4A
Former ID
DIB005595
Drug Name
BPS-804
Synonyms
Anti-sclerostin antibody (osteoporosis/hypophophatasia), Novartis
Drug Type
Antibody
Indication Metabolic bone disease [ICD10:E50-E64, E70-E90] Phase 2 [524231]
Company
Novartis AG
Target and Pathway
Target(s) Sclerostin Target Info [550150]
KEGG Pathway Wnt signaling pathway
NetPath Pathway TWEAK Signaling Pathway
Reactome TCF dependent signaling in response to WNT
Negative regulation of TCF-dependent signaling by WNT ligand antagonists
References
Ref 524231ClinicalTrials.gov (NCT01806610) Study of Safety and Tolerability of BPS804 in Patients With Late-stage Chronic Kidney Disease. U.S. National Institutes of Health.
Ref 550150WO patent application no. 2010,1001,79, Self-forming gel system for sustained drug delivery.

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