Drug Information

Drug General Information
Drug ID
D0Y3AZ
Former ID
DNCL003125
Drug Name
MK-2637
Indication Schizophrenia [ICD9: 295; ICD10:F20] Phase 1 [522716]
Company
Merck
Target and Pathway
Target(s) Sodium- and chloride-dependent glycine transporter 1 Target Info Modulator [532944]
Reactome Na+/Cl- dependent neurotransmitter transporters
WikiPathways NRF2 pathway
References
Ref 522716ClinicalTrials.gov (NCT00934466) Study of the Effect of Single Doses of MK2637 and Dextromethorphan on Cerebral Cortex Excitability (2637-008). U.S. National Institutes of Health.
Ref 532944Characterization of the novel GlyT1 PET tracer [18F]MK-6577 in humans. Synapse. 2015 Jan;69(1):33-40.

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