Drug General Information
Drug ID	D0Z0VF
Former ID	DNC012953
Drug Name	(S)-2-amino-2-phenylpropanoic acid
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[527946]
Structure		Download 2D MOL 3D MOL
Formula	C9H11NO2
Canonical SMILES	CC(C1=CC=CC=C1)(C(=O)O)N
InChI	1S/C9H11NO2/c1-9(10,8(11)12)7-5-3-2-4-6-7/h2-6H,10H2,1H3,(H,11,12)
InChIKey	HTCSFFGLRQDZDE-UHFFFAOYSA-N
PubChem Compound ID	853461
Target and Pathway
Target(s)	Voltage-dependent calcium channel subunit alpha-2/delta-1	Target Info	Inhibitor	[527946]
KEGG Pathway	MAPK signaling pathway
	Cardiac muscle contraction
	Adrenergic signaling in cardiomyocytes
	Oxytocin signaling pathway
	Hypertrophic cardiomyopathy (HCM)
	Arrhythmogenic right ventricular cardiomyopathy (ARVC)
	Dilated cardiomyopathy
PANTHER Pathway	Muscarinic acetylcholine receptor 2 and 4 signaling pathway
WikiPathways	Arrhythmogenic Right Ventricular Cardiomyopathy
	miR-targeted genes in muscle cell - TarBase
	miR-targeted genes in lymphocytes - TarBase
References
Ref 527946	Bioorg Med Chem Lett. 2006 Mar 1;16(5):1138-41. Epub 2005 Dec 27.Structure-activity relationships of alpha-amino acid ligands for the alpha2delta subunit of voltage-gated calcium channels.
Ref 527946	Bioorg Med Chem Lett. 2006 Mar 1;16(5):1138-41. Epub 2005 Dec 27.Structure-activity relationships of alpha-amino acid ligands for the alpha2delta subunit of voltage-gated calcium channels.

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