Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| Cathepsin K --- MEP | 2-Cyano-4-[(spiro[2.5]oct-6-ylmethyl)-amino]-pyrimidine-5-carboxylic acid (1-methyl-4-phenyl-piperidin-4-ylmethyl)-amide | Drug Info |
| Cathepsin K --- MEP | N-((S)-3-cyclohexyl-1-((4S,7R)-7-methyl-3-oxo-1-(pyridin-2-ylsulfonyl)azepan-4-ylamino)-1-oxopropan-2-yl)furan-2-carboxamide | Drug Info |
| Cathepsin K --- MEP | 5-Methyl-1-phenyl-1H-pyrazole-4-carboxylic acid {(S)-2-cyclohexyl-1-[2-(4-methoxy-phenylamino)-ethylcarbamoyl]-ethyl}-amide | Drug Info |
| Cathepsin K --- MEP | 3-Phenyl-propionic acid (2S,3S)-3-((S)-2-benzyloxycarbonylamino-3-phenyl-propionylamino)-4-oxo-azetidin-2-yl ester | Drug Info |
| Cathepsin K --- MEP | N-[1-(2S-Ethyl-4-oxo-tetrahydro-furan-3S-ylcarbamoyl)-2S-(1-methyl-cyclopentyl)-ethyl]-4-(pyridine-3-sulfonylamino)-benzamide | Drug Info |
| Cathepsin K --- MEP | N-[1-((S)-(S)-4-Benzoyl-6-(S)-oxo-hexahydro-pyrrolo[3,2-b]pyrrole-1-carbonyl)-3-methyl-butyl]-4-dimethylamino-benzamide | Drug Info |
| Cathepsin K --- MEP | 6-(4-chlorobenzyl)-7-phenethyl-7H-pyrrolo[2,3-d]pyrimidine-2-carbonitrile | Drug Info |
| Cathepsin K --- MEP | (R,S)-4-methyl-2-[4'-(2-piperazin-1-yl-thiazol-4-yl)-biphenyl-3-yl]-pentanoic acid cyanomethyl-amide | Drug Info |
| Cathepsin K --- MEP | 6-[4-(4-Acetyl-piperazin-1-yl)-phenoxymethyl]-7-[2-(4,4-difluoro-cyclohexyl)-ethyl]-7Hpyrrolo[2,3-d]pyrimidine-2-carbonitrile | Drug Info |
| Cathepsin K --- MEP | 2-Cyano-4-[(spiro[2.5]oct-6-ylmethyl)-amino]-pyrimidine-5-carboxylic acid ((S)-1-benzyl-2-pyrrolidin-1-yl-ethyl)-amide | Drug Info |
| Cathepsin K --- MEP | N-((S)-4-methyl-1-((4S,7R)-7-methyl-3-oxo-1-(pyridin-2-ylsulfonyl)azepan-4-ylamino)-1-oxopentan-2-yl)furan-2-carboxamide | Drug Info |
| Cathepsin K --- MEP | 2,2-dimethyl-3-phenylpropyl(S)-1,2-dioxo-1-((R)-1-phenylethylamino)heptan-3-ylcarbamate | Drug Info |
| Cathepsin K --- MEP | (S)-N-(cyanomethyl)-4-methyl-2-((S)-2,2,2-trifluoro-1-(4-phenoxyphenyl)ethylamino)pentanamide | Drug Info |
| Cathepsin K --- MEP | N-[1-(2S-Ethyl-4-oxo-tetrahydro-furan-3S-ylcarbamoyl)-2S-(1-methyl-cyclopentyl)-ethyl]-4-methanesulfonylamino-3-methoxy-benzamide | Drug Info |
| Cathepsin K --- MEP | (S)-N-((R)-2-(benzyloxy)-1-cyanoethyl)-2-(2-(4-chlorophenoxy)-2-methylpropanamido)-4-methylpentanamide | Drug Info |
| Cathepsin K --- MEP | 2-(cyclopentylmethyl)-N-(3-methyl-1-(4-(trifluoromethoxy)phenylamino)butan-2-yl)-4-morpholino-4-oxobutanamide | Drug Info |
| Cathepsin K --- MEP | (S)-N-(1-(2-(4-fluorophenylamino)ethylamino)-4-methyl-1-oxopentan-2-yl)-3-methylbenzamide | Drug Info |
| Cathepsin K --- MEP | benzyl (S)-1-((R)-2-(benzyloxy)-1-cyanoethylamino)-4-methyl-1-oxopentan-2-ylcarbamate | Drug Info |
| Cathepsin K --- MEP | [(S)-1-((S)-3-Benzyloxy-2-oxo-1-phenethyl-propylcarbamoyl)-3-methyl-butyl]-carbamic acid benzyl ester | Drug Info |
| Cathepsin K --- MEP | N-((S)-1-((R)-2-(benzyloxy)-1-cyanoethylamino)-4-methyl-1-oxopentan-2-yl)-1-methyl-1H-indole-2-carboxamide | Drug Info |
| Cathepsin K --- MEP | [(S)-1-((R)-1-Phenyl-ethylaminooxalyl)-pentyl]-carbamic acid (S)-indan-1-yl ester | Drug Info |
| Cathepsin K --- MEP | N-{(S)-1-[2-(4-Isobutoxy-phenylamino)-ethylcarbamoyl]-3-methyl-butyl}-4-methoxy-benzamide | Drug Info |
| Cathepsin K --- MEP | (S)-N-(3-cyclohexyl-1-oxo-1-(2-(4-(trifluoromethoxy)phenylamino)ethylamino)propan-2-yl)furan-2-carboxamide | Drug Info |
| Cathepsin K --- MEP | benzyl (S)-1-((R)-2-tert-butoxy-1-cyanoethylamino)-4-methyl-1-oxopentan-2-ylcarbamate | Drug Info |
| Cathepsin K --- MEP | [(S)-1-((R)-1-Phenyl-ethylaminooxalyl)-pentyl]-carbamic acid 1,3,3-trimethyl-bicyclo[2.2.1]hept-2-yl ester | Drug Info |
| Cathepsin K --- MEP | [(S)-1-((S)-1-Benzyl-2-phenylamino-ethylcarbamoyl)-3-methyl-butyl]-carbamic acid benzyl ester | Drug Info |
| Cathepsin K --- MEP | 9-Cyclopentyl-6-[2-(3-imidazol-1-yl-propoxy)-phenylamino]-9H-purine-2-carbonitrile | Drug Info |
| Cathepsin K --- MEP | N-(benzyloxycarbonyl)-phenylalanyl-glycine-nitrile | Drug Info |
| Cathepsin K --- MEP | [(S)-1-((2S,3R)-2-Benzenesulfonyl-4-oxo-azetidin-3-ylcarbamoyl)-2-phenyl-ethyl]-carbamic acid benzyl ester | Drug Info |
| Cathepsin K --- MEP | N-[(3R)-1-cyano-3-pyrrolidinyl]-2,5-bis(methyloxy)benzenesulfonamide | Drug Info |
| Cathepsin K --- MEP | (S)-N-((S)-3-cyclohexyl-1-oxo-1-((S)-1-(4-(trifluoromethoxy)phenylamino)propan-2-ylamino)propan-2-yl)-tetrahydrofuran-2-carboxamide | Drug Info |
| Cathepsin K --- MEP | {(S)-3-Methyl-1-[4-oxo-1-(4-phenoxy-benzoyl)-pyrrolidin-3-ylcarbamoyl]-butyl}-carbamic acid benzyl ester | Drug Info |
| Cathepsin K --- MEP | {1-[3-(2-Benzyloxycarbonylamino-4-methyl-pentanoylamino)-4-oxo-pyrrolidine-1-carbonyl]-3-methyl-butyl}-carbamic acid benzyl ester | Drug Info |
| Cathepsin K --- MEP | 9-Cyclopentyl-6-(2-{4-[2-(4-methyl-piperazin-1-yl)-ethoxy]-benzyloxy}-phenylamino)-9H-purine-2-carbonitrile | Drug Info |
| Cathepsin K --- MEP | N-{(S)-1-[2-(4-Cyclopentylmethoxy-phenylamino)-ethylcarbamoyl]-3-methyl-butyl}-4-methoxy-benzamide | Drug Info |
| Cathepsin K --- MEP | 2-cyano-4-(2,2-dimethyl-propylamino)-pyrimidine-5-carboxylic acid {2-[4-(4-methyl-piperazin-1-yl)-phenyl]-ethyl}-amide | Drug Info |
| Cathepsin K --- MEP | (S)-N-(3-(3-chlorophenyl)-1-(cyanomethylamino)-1-oxopropan-2-yl)-1,3-dimethyl-1H-pyrazole-4-carboxamide | Drug Info |
| Cathepsin K --- MEP | CHEMBL450061 | Drug Info |
| Cathepsin K --- MEP | [(S)-1-((3R,4S)-2-Oxo-4-phenylsulfanyl-azetidin-3-ylcarbamoyl)-2-phenyl-ethyl]-carbamic acid benzyl ester | Drug Info |
| Cathepsin K --- MEP | N-((S)-1-((4S,7R)-7-methyl-3-oxo-1-picolinoylazepan-4-ylamino)-3-(1-methylcyclohexyl)-1-oxopropan-2-yl)furan-2-carboxamide | Drug Info |
| Cathepsin K --- MEP | N-((S)-3-cyclohexyl-1-oxo-1-(2-(4-(trifluoromethoxy)phenylamino)ethylamino)propan-2-yl)-5-(3-(trifluoromethyl)phenyl)furan-2-carboxamide | Drug Info |
| Cathepsin K --- MEP | (S)-N-(1-(2-(5-chloroindolin-1-yl)ethylamino)-4-methyl-1-oxopentan-2-yl)-3-methylbenzamide | Drug Info |
| Cathepsin K --- MEP | [(S)-1-((2S,3S)-2-Benzyloxy-4-oxo-azetidin-3-ylcarbamoyl)-2-phenyl-ethyl]-carbamic acid benzyl ester | Drug Info |
| Cathepsin K --- MEP | 5-Bromo-4-[2-(1-methyl-piperidin-4-yl)-ethoxy]-6-[(spiro[2.5]oct-6-ylmethyl)-amino]-pyrimidine-2-carbonitrile | Drug Info |
| Cathepsin K --- MEP | benzyl (S)-1-((S)-1-cyano-2-(4-methoxyphenyl)ethylamino)-4-methyl-1-oxopentan-2-ylcarbamate | Drug Info |
| Cathepsin K --- MEP | (S)-N-(3-(3-(1,3,4-thiadiazol-2-yl)phenyl)-1-(cyanomethylamino)-1-oxopropan-2-yl)-3-tert-butyl-1-methyl-1H-pyrazole-5-carboxamide | Drug Info |
| Cathepsin K --- MEP | (S)-3-tert-butyl-N-(1-(cyanomethylamino)-3-(3-(5-(methoxymethyl)-1,3,4-oxadiazol-2-yl)phenyl)-1-oxopropan-2-yl)-1-methyl-1H-pyrazole-5-carboxamide | Drug Info |
| Cathepsin K --- MEP | N-{(S)-3-Cyclohexyl-1-[2-(4-methoxy-phenylamino)-ethylcarbamoyl]-propyl}-3-methyl-benzamide | Drug Info |
| Cathepsin K --- MEP | 6-(cyclohexylamino)-9-(2-(4-methylpiperazin-1-yl)ethyl)-9H-purine-2-carbonitrile | Drug Info |
| Cathepsin K --- MEP | 2-cyano-4-cyclohexylamino-pyrimidine-5-carboxylic acid {2-[4-(4-methylpiperazin-1-yl)-phenyl]-ethyl}-amide | Drug Info |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.