Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| EGFR3 --- HER2 | 4-(3-bromo-4-methylphenylamino)-6,7-dimethoxyquinoline-3-carbonitrile | Drug Info |
| EGFR3 --- HER2 | 4-(1-(3-fluorobenzyl)-1H-indazol-5-ylamino)-6-aminopyrimidine-5-carbaldehyde oxime | Drug Info |
| EGFR3 --- HER2 | 2-(5-(4-Bromophenyl)-3-(4-chlorophenyl)-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one | Drug Info |
| EGFR3 --- HER2 | (3R,5S)-5-((4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)thieno[3,2-d]pyrimidin-6-yl)ethynyl)pyrrolidin-3-yl ethyl(methyl)carbamate | Drug Info |
| EGFR3 --- HER2 | 4-Dimethylamino-but-2-enoic acid {4-[3-chloro-4-(pyrimidin-2-ylsulfanyl)-phenylamino]-3-cyano-7-methoxy-quinolin-6-yl}-amide | Drug Info |
| EGFR3 --- HER2 | N-(3-chloro-4-(3-fluorobenzyloxy)phenyl)-6-methyl-5-((4-((2-(methylsulfonyl)ethylamino)methyl)phenyl)ethynyl)pyrimidin-4-amine | Drug Info |
| EGFR3 --- HER2 | 2-(2-(4-Bromobenzylidene)hydrazinyl)thiazol-4(5H)-one | Drug Info |
| EGFR3 --- HER2 | N-(3-chloro-4-(3-fluorobenzyloxy)phenyl)-5-((4-((isopropylamino)methyl)phenyl)ethynyl)-6-methylpyrimidin-4-amine | Drug Info |
| EGFR3 --- HER2 | Tyrosol caffeate | Drug Info |
| EGFR3 --- HER2 | 4-(3-Chloro-4-fluoro-phenylamino)-5-[1-[3-methyl-5-(morpholine-4-carbonyl)-1H-pyrrol-2-yl]-meth-(Z)-ylidene]-5,7-dihydro-pyrrolo[2,3-d]pyrimidin-6-one | Drug Info |
| EGFR3 --- HER2 | 2-(4-Fluorophenyl)-N-(phenylsulfonyl)acetamide | Drug Info |
| EGFR3 --- HER2 | 7-(4-(4-Fluorobenzylamino)-7-methoxyquinazolin-6-yloxy)-N-hydroxyheptanamide | Drug Info |
| EGFR3 --- HER2 | 4-(3-bromophenylamino)-6,7-dimethoxyquinoline-3-carbonitrile | Drug Info |
| EGFR3 --- HER2 | 5-((4-aminopiperidin-1-yl)methyl)-N-(3-bromophenyl)pyrrolo[1,2-f][1,2,4]triazin-4-amine | Drug Info |
| EGFR3 --- HER2 | [4-[[1-(3-fluorophenyl)methyl]-1H-indazol-5-ylamino]-5-ethyl-pyrrolo[2,1-f][1,2,4]triazin-6-yl]-carbamic acid,(3S)-3-morpholinylmethyl ester | Drug Info |
| EGFR3 --- HER2 | 1-(2-chloroethyl)-3-{[4-(3-methylphenyl)amino]quinazolin-6-yl}urea | Drug Info |
| EGFR3 --- HER2 | 5-(4-(3-Ethynylphenylamino)-7-methoxyquinazolin-6-yloxy)-N-hydroxypentanamide | Drug Info |
| EGFR3 --- HER2 | (R)-methyl 2-((4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)thieno[3,2-d]pyrimidin-6-yl)ethynyl)pyrrolidine-1-carboxylate | Drug Info |
| EGFR3 --- HER2 | (1-Benzyl-1H-indazol-5-yl)-{6-[2-(2-methanesulfonyl-ethylamino)-thiazol-4-yl]-quinazolin-4-yl}-amine | Drug Info |
| EGFR3 --- HER2 | 2-(3,5-Diphenyl-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one | Drug Info |
| EGFR3 --- HER2 | 4-(1-(3-fluorobenzyl)indolin-5-ylamino)-6-aminopyrimidine-5-carbaldehyde O-methyl oxime | Drug Info |
| EGFR3 --- HER2 | 4-Dimethylamino-but-2-enoic acid {4-[3-chloro-4-((R)-1-phenyl-ethoxy)-phenylamino]-3-cyano-7-ethoxy-quinolin-6-yl}-amide | Drug Info |
| EGFR3 --- HER2 | 1-(5-Bromo-2-hydroxybenzyl)-1-(4-hydroxybenzyl)-3-phenylthiourea | Drug Info |
| EGFR3 --- HER2 | N-(4-(3-bromophenylamino)-3-cyanoquinolin-6-yl)acrylamide | Drug Info |
| EGFR3 --- HER2 | (E)-3-[3-(2-Acetylamino-phenylsulfanylmethyl)-4-hydroxy-5-methoxy-phenyl]-2-cyano-acrylamide | Drug Info |
| EGFR3 --- HER2 | 3-(4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)-6-methylpyrimidin-5-yl)-1-(4-ethylpiperazin-1-yl)-2-fluoroprop-2-en-1-one | Drug Info |
| EGFR3 --- HER2 | 3-(4-(3-chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-yloxy)-N-hydroxypropanamide | Drug Info |
| EGFR3 --- HER2 | 3-(4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)-6-methylpyrimidin-5-yl)-N-(2-morpholinoethyl)acrylamide | Drug Info |
| EGFR3 --- HER2 | N-[4-[(3-chloro-4-fluorophenyl)amino]-6-quinazolinyl]-5-(4-diethylamino)-2-pentynamide | Drug Info |
| EGFR3 --- HER2 | 7-(4-(3-Chloro-4-fluorobenzylamino)-7-methoxyquinazolin-6-yloxy)-hydroxyheptanamide | Drug Info |
| EGFR3 --- HER2 | N-(1-(3-fluorobenzyl)-1H-indazol-5-yl)-5-((6-methyl-1,4-diazepan-1-yl)methyl)pyrrolo[1,2-f][1,2,4]triazin-4-amine | Drug Info |
| EGFR3 --- HER2 | [3-Chloro-4-(pyridin-2-ylmethoxy)-phenyl]-[5-(tetrahydro-pyran-4-yloxy)-quinazolin-4-yl]-amine | Drug Info |
| EGFR3 --- HER2 | {4-(1-Benzyl-1H-indazol-5-ylamino)-5-ethyl-pyrrolo[2,1-f][1,2,4]triazin-6-yl}-carbamic acid trans-4-aminocyclohexyl ester | Drug Info |
| EGFR3 --- HER2 | 4-(Bis(2-chloroethyl)amino)-N-(4-methoxyphenyl)benzamide | Drug Info |
| EGFR3 --- HER2 | 2-(2-(5-Chloro-2-hydroxybenzylidene)hydrazinyl)thiazol-4(5H)-one | Drug Info |
| EGFR3 --- HER2 | 4-(1-(3-fluorobenzyl)-1H-indazol-5-ylamino)-6-aminopyrimidine-5-carbaldehyde O-isopropyl oxime | Drug Info |
| EGFR3 --- HER2 | 4-Dimethylamino-but-2-enoic acid {4-[3-chloro-4-((S)-indan-1-yloxy)-phenylamino]-3-cyano-7-ethoxy-quinolin-6-yl}-amide | Drug Info |
| EGFR3 --- HER2 | 3-(2-(1,2-oxazepan-2-yl)ethoxy)-N-(3-chloro-4-(pyridin-2-ylmethoxy)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine | Drug Info |
| EGFR3 --- HER2 | 4-(3-Chloro-4-fluoro-phenylamino)-5-[1-[3-methyl-5-(4-methyl-piperazine-1-carbonyl)-1H-pyrrol-2-yl]-meth-(Z)-ylidene]-5,7-dihydro-pyrrolo[2,3-d]pyrimidin-6-one | Drug Info |
| EGFR3 --- HER2 | 4-(2-isopropylphenylamino)-6,7-dimethoxyquinoline-3-carbonitrile | Drug Info |
| EGFR3 --- HER2 | 5-[4-(3-Ethynyl-phenylamino)-6-oxo-6,7-dihydro-pyrrolo[2,3-d]pyrimidin-(5Z)-ylidenemethyl]-4-methyl-1H-pyrrole-2-carboxylic acid (2-morpholin-4-yl-ethyl)-amide | Drug Info |
| EGFR3 --- HER2 | 2-(5-(4-Chlorophenyl)-3-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one | Drug Info |
| EGFR3 --- HER2 | 5-(4-(benzylamino)but-1-ynyl)-N-(3-chloro-4-(3-fluorobenzyloxy)phenyl)-6-methylpyrimidin-4-amine | Drug Info |
| EGFR3 --- HER2 | 6-(5-((2-(Methylsulfinyl)ethylamino)methyl)furan-2-yl)-N-(4-(3-fluorobenzyloxy)3-chlorophenyl)-4-quinazolinamine tosylate | Drug Info |
| EGFR3 --- HER2 | 4-(Bis(2-chloroethyl)amino)-N-(1-naphthyl)benzamide | Drug Info |
| EGFR3 --- HER2 | (E)-3-[3-(Benzooxazol-2-ylsulfanylmethyl)-4-hydroxy-5-methoxy-phenyl]-2-cyano-acrylamide | Drug Info |
| EGFR3 --- HER2 | GW684626B | Drug Info |
| EGFR3 --- HER2 | 4-(1-(3-fluorobenzyl)-1H-indazol-5-ylamino)-6-aminopyrimidine-5-carbaldehyde O-2-methoxyethyl oxime | Drug Info |
| EGFR3 --- HER2 | N-(3-chloro-4-(3-fluorobenzyloxy)phenyl)-6-methyl-5-((5-(pyrrolidin-1-ylmethyl)thiazol-2-yl)ethynyl)pyrimidin-4-amine | Drug Info |
| EGFR3 --- HER2 | (E)-3-[3-(2-Chloro-benzylsulfanylmethyl)-4-hydroxy-5-methoxy-phenyl]-2-cyano-acrylamide | Drug Info |
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