Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| VEGFR2 --- CSrc | 4-(7-amino-3-(4-(4-methylpiperazin-1-yl)phenyl)pyrazolo[1,5-a]pyrimidin-6-yl)phenol | Drug Info |
| VEGFR2 --- CSrc | N-(3-(1-(6-(trans-4-aminocyclohexylamino)pyrimidin-4-yl)-1H-benzo[d]imidazol-2-ylamino)-4-methylphenyl)-3-(trifluoromethyl)benzamide | Drug Info |
| VEGFR2 --- CSrc | 4-methyl-3-(1-(6-(3-(4-methylpiperazin-1-yl)propylamino)pyrimidin-4-yl)-1H-benzo[d]imidazol-2-ylamino)-N-m-tolylbenzamide | Drug Info |
| VEGFR2 --- CSrc | N-(3-(1-(6-aminopyrimidin-4-yl)-1H-benzo[d]imidazol-2-ylamino)-4-methylphenyl)-3-(4-methylpiperazin-1-yl)-5-(trifluoromethyl)benzamide | Drug Info |
| VEGFR2 --- CSrc | CHEMBL262721 | Drug Info |
| VEGFR2 --- CSrc | N-(5-chloro-2-methoxypyridin-4-yl)-7-(3-morpholinopropoxy)-5-(tetrahydro-2H-pyran-4-yloxy)quinazolin-4-amine | Drug Info |
| VEGFR2 --- CSrc | 3-(1-(6-aminopyrimidin-4-yl)-1H-benzo[d]imidazol-2-ylamino)-N-(3-methoxyphenyl)-4-methylbenzamide | Drug Info |
| VEGFR2 --- CSrc | 5-Ethanesulfonyl-3-[1-{3-[3-(4-methyl-piperazin-1-yl)-propyl]-4,5,6,7-tetrahydro-1H-indol-2-yl}-meth-(Z)-ylidene]-1,3-dihydro-indol-2-one | Drug Info |
| VEGFR2 --- CSrc | 1-(4-(7-amino-3-(3-(4-methylpiperazin-1-yl)phenyl)pyrazolo[1,5-a]pyrimidin-6-yl)phenyl)-3-(cyclohexylmethyl)urea | Drug Info |
| VEGFR2 --- CSrc | CHEMBL386996 | Drug Info |
| VEGFR2 --- CSrc | N-(3-(1-(6-(4-(dimethylamino)butylamino)pyrimidin-4-yl)-1H-benzo[d]imidazol-2-ylamino)-4-methylphenyl)-3-(trifluoromethyl)benzamide | Drug Info |
| VEGFR2 --- CSrc | 3-(7-amino-3-(4-(4-methylpiperazin-1-yl)phenyl)pyrazolo[1,5-a]pyrimidin-6-yl)phenol | Drug Info |
| VEGFR2 --- CSrc | 6-(2,6-dimethylphenyl)-2-((4-((3-(1-piperidinyl)propyl)oxy)phenyl)amino)-pyrimido[5',4':5,6]pyrimido[1,2-a]benzimidazol-5(6H)-one | Drug Info |
| VEGFR2 --- CSrc | CHEMBL436968 | Drug Info |
| VEGFR2 --- CSrc | 3-(1-(6-(4-(dimethylamino)butylamino)pyrimidin-4-yl)-1H-benzo[d]imidazol-2-ylamino)-4-methyl-N-(3-(trifluoromethyl)phenyl)benzamide | Drug Info |
| VEGFR2 --- CSrc | N-(2-chloro-5-methoxyphenyl)-7-(3-morpholin-4-ylpropoxy)-5-(tetrahydro-2H-pyran-4-yloxy)quinazolin-4-amine | Drug Info |
| VEGFR2 --- CSrc | 2-((4-((2-(dimethylamino)ethyl)oxy)-phenyl)amino)-6-(2,6-dimethylphenyl)-pyrimido[5',4':5,6]pyrimido[1,2-a]benzimidazol-5(6H)-one | Drug Info |
| VEGFR2 --- CSrc | N-(4-(7-amino-3-(4-(4-methylpiperazin-1-yl)phenyl)pyrazolo[1,5-a]pyrimidin-6-yl)phenyl)-4-(trifluoromethyl)benzamide | Drug Info |
| VEGFR2 --- CSrc | 4-{1-[(Benzyloxy)methyl]-1H-indol-3-yl}-3-(3,4,5-trimethoxyphenyl)-1,5-dihydro-2H-pyrrole-2-one | Drug Info |
| VEGFR2 --- CSrc | N-(4-methyl-3-(1-(6-(2-(pyrrolidin-2-yl)ethylamino)pyrimidin-4-yl)-1H-benzo[d]imidazol-2-ylamino)phenyl)-3-(trifluoromethyl)benzamide | Drug Info |
| VEGFR2 --- CSrc | [6-Methoxy-7-(3-morpholin-4-yl-propoxy)-quinazolin-4-yl]-(1-methyl-1H-indol-4-yl)-amine | Drug Info |
| VEGFR2 --- CSrc | isobutyl4-(7-amino-3-(3-(4-methylpiperazin-1-yl)phenyl)pyrazolo[1,5-a]pyrimidin-6-yl)-3-methylphenylcarbamate | Drug Info |
| VEGFR2 --- CSrc | 6-(2,6-dimethylphenyl)-2-((3-(methoxy)-4-(4-methyl-1-piperazinyl)phenyl)-amino)pyrimido[5',4':5,6]pyrimido[1,2-a]benzimidazol-5(6H)-one | Drug Info |
| VEGFR2 --- CSrc | 2,6-dimethylphenyl (2,5-bis(methyloxy)phenyl)methyl(2-((4-(4-methyl-1-piperazinyl)phenyl)amino)-4-pyrimidinyl)carbamate | Drug Info |
| VEGFR2 --- CSrc | Benzo[1,3]dioxol-4-yl-[6-methoxy-7-(3-morpholin-4-yl-propoxy)-quinazolin-4-yl]-amine | Drug Info |
| VEGFR2 --- CSrc | N-(4-(7-amino-3-(3-(4-methylpiperazin-1-yl)phenyl)pyrazolo[1,5-a]pyrimidin-6-yl)phenyl)-3-cyclopentylpropanamide | Drug Info |
| VEGFR2 --- CSrc | [6-Methoxy-7-(3-morpholin-4-yl-propoxy)-quinazolin-4-yl]-(4-methoxy-phenyl)-amine | Drug Info |
| VEGFR2 --- CSrc | N-(4-methyl-3-(1-(6-(2-(pyridin-2-yl)ethylamino)pyrimidin-4-yl)-1H-benzo[d]imidazol-2-ylamino)phenyl)-3-(trifluoromethyl)benzamide | Drug Info |
| VEGFR2 --- CSrc | isobutyl4-(7-amino-3-(3-(piperazin-1-yl)phenyl)pyrazolo[1,5-a]pyrimidin-6-yl)phenylcarbamate | Drug Info |
| VEGFR2 --- CSrc | N-(3-chloro-6-methoxypyridin-2-yl)-7-(3-morpholinopropoxy)-5-(tetrahydro-2H-pyran-4-yloxy)quinazolin-4-amine | Drug Info |
| VEGFR2 --- CSrc | N-(3-(1-(6-aminopyrimidin-4-yl)-1H-benzo[d]imidazol-2-ylamino)-4-methylphenyl)-3-tert-butyl-1-methyl-1H-pyrazole-5-carboxamide | Drug Info |
| VEGFR2 --- CSrc | CHEMBL371688 | Drug Info |
| VEGFR2 --- CSrc | N-(3-(1-(6-chloropyrimidin-4-yl)-1H-benzo[d]imidazol-2-ylamino)-4-methylphenyl)-3-(trifluoromethyl)benzamide | Drug Info |
| VEGFR2 --- CSrc | phenyl4-(7-amino-3-(3-(4-methylpiperazin-1-yl)phenyl)pyrazolo[1,5-a]pyrimidin-6-yl)phenylcarbamate | Drug Info |
| VEGFR2 --- CSrc | N-(3-(1-(6-aminopyrimidin-4-yl)-1H-benzo[d]imidazol-2-ylamino)-4-methylphenyl)-5-tert-butylthiophene-2-carboxamide | Drug Info |
| VEGFR2 --- CSrc | isobutyl4-(7-amino-3-(3-(4-methylpiperazin-1-yl)phenyl)pyrazolo[1,5-a]pyrimidin-6-yl)phenylcarbamate | Drug Info |
| VEGFR2 --- CSrc | N-(4-methyl-3-(1-(6-(3-(4-methylpiperazin-1-yl)propylamino)pyrimidin-4-yl)-1H-benzo[d]imidazol-2-ylamino)phenyl)-3-(trifluoromethyl)benzamide | Drug Info |
| VEGFR2 --- CSrc | N-(2-chloro-5-methoxyphenyl)-5-(cyclohexyloxy)-7-(3-morpholinopropoxy)quinazolin-4-amine | Drug Info |
| VEGFR2 --- CSrc | 2-(4-(6-(6-(2-(2-chloro-6-methylphenylamino)-1H-benzo[d]imidazol-1-yl)pyrimidin-4-ylamino)-2-methylpyrimidin-4-yl)piperazin-1-yl)ethanol | Drug Info |
| VEGFR2 --- CSrc | N-(3-(1-(6-aminopyrimidin-4-yl)-1H-benzo[d]imidazol-2-ylamino)-4-methylphenyl)-3-cyclopropyl-1H-pyrazole-5-carboxamide | Drug Info |
| VEGFR2 --- CSrc | 2-((3,5-dimethoxy)-4-((2-(4-morpholinyl)ethyl)oxy)phenyl)amino)-6-(2,6-dimethylphenyl)-pyrimido-[5',4':5,6]pyrimido[1,2-a]benzimidazol-5(6H)-one | Drug Info |
| VEGFR2 --- CSrc | N-(2-chloro-5-methoxyphenyl)-5-isopropoxy-7-(3-morpholinopropoxy)quinazolin-4-amine | Drug Info |
| VEGFR2 --- CSrc | 4-methyl-3-(1-(6-(2-(4-methylpiperazin-1-yl)ethylamino)pyrimidin-4-yl)-1H-benzo[d]imidazol-2-ylamino)-N-(3-(trifluoromethyl)phenyl)benzamide | Drug Info |
| VEGFR2 --- CSrc | 4-methyl-3-(1-(4-(3-(4-methylpiperazin-1-yl)propylamino)-1,3,5-triazin-2-yl)-1H-benzo[d]imidazol-2-ylamino)-N-(3-(trifluoromethyl)phenyl)benzamide | Drug Info |
| VEGFR2 --- CSrc | 2,6-dimethylphenyl-2,4-bis(methyloxy)phenyl(2-((3-fluoro-4-((2-(4-methyl-1-piperazinyl)ethyl)oxy)phenyl)amino)-4-pyrimidinyl)carbamate | Drug Info |
| VEGFR2 --- CSrc | N-(2-chloro-5-methoxypyridin-3-yl)-7-(3-morpholinopropoxy)-5-(tetrahydro-2H-pyran-4-yloxy)quinazolin-4-amine | Drug Info |
| VEGFR2 --- CSrc | N-(2-chloro-5-methoxypyridin-3-yl)-5-isopropoxy-7-(3-morpholinopropoxy)quinazolin-4-amine | Drug Info |
| VEGFR2 --- CSrc | 3-(1-(6-aminopyrimidin-4-yl)-1H-benzo[d]imidazol-2-ylamino)-N-(3-bromophenyl)-4-methylbenzamide | Drug Info |
| VEGFR2 --- CSrc | 3-(1-(6-(2-cyanoethylamino)pyrimidin-4-yl)-1H-benzo[d]imidazol-2-ylamino)-4-methyl-N-(3-(trifluoromethyl)phenyl)benzamide | Drug Info |
| VEGFR2 --- CSrc | CHEMBL426161 | Drug Info |
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