Target Information
| Target General Infomation | |||||
|---|---|---|---|---|---|
| Target ID |
T32282
|
||||
| Former ID |
TTDR00418
|
||||
| Target Name |
Prolactin
|
||||
| Gene Name |
PRL
|
||||
| Synonyms |
PRL
|
||||
| Target Type |
Discontinued
|
||||
| Disease | Multiple scierosis [ICD9: 340; ICD10: G35] | ||||
| Function |
Prolactin acts primarily on the mammary gland by promoting lactation.
|
||||
| BioChemical Class |
Hormone
|
||||
| UniProt ID | |||||
| Sequence |
MNIKGSPWKGSLLLLLVSNLLLCQSVAPLPICPGGAARCQVTLRDLFDRAVVLSHYIHNL
SSEMFSEFDKRYTHGRGFITKAINSCHTSSLATPEDKEQAQQMNQKDFLSLIVSILRSWN EPLYHLVTEVRGMQEAPEAILSKAVEIEEQTKRLLEGMELIVSQVHPETKENEIYPVWSG LPSLQMADEESRLSAYYNLLHCLRRDSHKIDNYLKLLKCRIIHNNNC |
||||
| Drugs and Mode of Action | |||||
| Target Expression Profile (TEP) and Drug Resistance Mutation (DRM) | |||||
| TEP | EXP Info | ||||
| Pathways | |||||
| KEGG Pathway | Cytokine-cytokine receptor interaction | ||||
| Neuroactive ligand-receptor interaction | |||||
| PI3K-Akt signaling pathway | |||||
| Jak-STAT signaling pathway | |||||
| Prolactin signaling pathway | |||||
| NetPath Pathway | IL2 Signaling Pathway | ||||
| Pathway Interaction Database | ErbB4 signaling events | ||||
| Signaling events mediated by PTP1B | |||||
| Glucocorticoid receptor regulatory network | |||||
| Validated nuclear estrogen receptor alpha network | |||||
| Reactome | Prolactin receptor signaling | ||||
| Amyloid formation | |||||
| Growth hormone receptor signaling | |||||
| WikiPathways | Prostaglandin Synthesis and Regulation | ||||
| EV release from cardiac cells and their functional effects | |||||
| Prolactin receptor signaling | |||||
| Growth hormone receptor signaling | |||||
| JAK/STAT | |||||
| References | |||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.