Drug Information

Drug General Information
Drug ID
DX2BA3
Drug Name
(R)-2-(benzo[c][1,2,5]thiadiazole-4-sulfonamido)-4-bromo-N-(2-phenylpropyl)benzamide
Synonyms
CHEMBL584063
Indication Discovery agent Investigative [1587926]
Formula
C22H19BrN4O3S2
Canonical SMILES
C[C@@H](CNC(=O)c1ccc(Br)cc1NS(=O)(=O)c2cccc3nsnc23)c4ccccc4
InChI
InChI=1S/C22H19BrN4O3S2/c1-14(15-6-3-2-4-7-15)13-24-22(28)17-11-10-16(23)12-19(17)27-32(29,30)20-9-5-8-18-21(20)26-31-25-18/h2-12,14,27H,13H2,1H3,(H,24,28)/t14-/m0/s1
InChIKey
JPSKEXDSISGXCN-AWEZNQCLSA-N
Target and Pathway
Target(s) Gastrin/cholecystokinin type B receptor Target Info [1587926]
Cholecystokinin receptor type A Target Info [1587926]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Gastric acid secretionhsa04020:Calcium signaling pathway
Insulin secretion
Pancreatic secretion
PANTHER Pathway CCKR signaling map ST
PathWhiz Pathway Gastric Acid Production
Reactome Peptide ligand-binding receptors
G alpha (q) signalling events
Gastrin-CREB signalling pathway via PKC and MAPKR-HSA-375276:Peptide ligand-binding receptors
WikiPathways GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
Secretion of Hydrochloric Acid in Parietal Cells
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
GPCRs, OtherWP455:GPCRs, Class A Rhodopsin-like
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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