TTD | Drug: D06ZDF

Drug General Information
Drug ID	D06ZDF
Former ID	DIB020319
Drug Name	ME67
Synonyms	EM-B enolether
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[538925]
Structure		Download 2D MOL
Formula	C37H65NO11
InChI	InChI=1S/C37H65NO11/c1-14-26-20(4)28(39)21(5)30-18(2)16-37(10,49-30)33(48-35-29(40)25(38(11)12)15-19(3)44-35)22(6)31(23(7)34(42)46-26)47-27-17-36(9,43-13)32(41)24(8)45-27/h19-29,31-33,35,39-41H,14-17H2,1-13H3/t19-,20-,21-,22+,23-,24+,25+,26-,27+,28+,29-,31+,32+,33-,35+,36-,37+/m1/s1
InChIKey	RVWZXQUMKFWVJM-GKMPZCCESA-N
PubChem Compound ID	10032648
PubChem Substance ID	15014216, 53838389, 78112674, 135652705, 136352737
Target and Pathway
Target(s)	Motilin receptor	Target Info	Agonist	[527468]
KEGG Pathway	Neuroactive ligand-receptor interaction
Reactome	Peptide ligand-binding receptors
Reactome	G alpha (q) signalling events
WikiPathways	GPCRs, Class A Rhodopsin-like
	Gastrin-CREB signalling pathway via PKC and MAPK
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 538925	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1449).
Ref 527468	Desensitization of the human motilin receptor by motilides. J Pharmacol Exp Ther. 2005 Jun;313(3):1397-405. Epub 2005 Mar 11.

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Drug Information