Drug General Information
Drug ID
D0C6DT
Former ID
DAP000726
Drug Name
Esomeprazole
Synonyms
AULCER; Antra; Audazol; Axagon; Belmazol; Ceprandal; Danlox; Demeprazol; Desec; Dizprazol; Dudencer; Elgam; Emeproton; Emilok; Epirazole; Erbolin; Esomeprazol; Esomeprazolum; Esomperazole; Esopral; Exter; Gasec; Gastrimut; Gastroloc; Gibancer; Indurgan; Inhibitron; Inhipump; Lensor; Logastric; Lomac; Losec; Lucen; Mepral; Miol; Miracid; Mopral; Morecon; Nexiam; Nexium; Nilsec; Nopramin; Nuclosina; OMEP; OMZ; Ocid; Olexin; Olit; Omapren; Omebeta; Omed; Omegast; Omepradex; Omepral; Omeprazol; Omeprazole; Omeprazolum; Omeprazon; Omeprazone; Omeprol; Omesek; Omez; Omezol; Omezolan; Omid; Omisec; Omizac; Ompanyt; Ortanol; Osiren; Ozoken; Paprazol; Parizac; Pepticum; Pepticus; Peptilcer; Prazentol; Prazidec; Prazolit; Prilosec; Procelac; Proclor; Prysma; Ramezol; Regulacid; Result; Sanamidol; Secrepina; Ulceral; Ulcesep; Ulcometion; Ulcozol; Ulcsep; Ulsen; Ultop; Ulzol; Victrix; Zefxon; Zegerid; Zepral; Zimor; Zoltum; Antra MUPS; Inexium paranova; Nexium IV; Omeprazole magnesium; Prilosec OTC; Tedec Ulceral; O0359; Omebeta 20; AGI-010; Axagon (TN); DM-3458; Esomeprazole (INN); Esomeprazole [INN:BAN]; Esopral (TN); H 168-68; H 168/68; Inexium paranova (TN); Lucen (TN); Nexiam (TN); Nexium (TN); Omeprazol [INN-Spanish]; Omeprazole delayed-release; Omeprazolum [INN-Latin]; Prilosec (TN); SAN-15; Sompraz (TN); Zoleri (TN); H-168/68; Omeprazole (JAN/USP/INN); Omeprazole [USAN:INN:BAN:JAN]; Losec, Omesec, Prilosec, Zegerid, Omeprazole; (-)-Omeprazole; (S)-(-)-Omeprazole; (S)-Omeprazole; 2-(((3,5-Dimethyl-4-methoxy-2-pyridyl)methyl)sulfinyl)-5-methoxy-1H-benzimidazole; 2-({[3,5-dimethyl-4-(methyloxy)pyridin-2-yl]methyl}sulfinyl)-5-(methyloxy)-1H-benzimidazole; 5-Methoxy-2-(((4-methoxy-3,5-dimethyl-2-pyridyl)methyl)sulfinyl)benzimidazole; 5-Methoxy-2-((S)-((4-methoxy-3,5-dimethyl-2-pyridyl)methyl)sulfinyl)benzimidazole; 5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole; 5-Methoxy-2[(4-methoxy-3,5-dimethyl-2-pyridyl)methylsulfinyl]-1H-benzimidazole; 5-methoxy-2-{(S)-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole; 5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1-methyl-1H-benzimidazole; 5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole; 6-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]-1H-benzimidazole; 6-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole
Drug Type
Small molecular drug
Indication Peptic ulcer [ICD9: 531-534; ICD10:K25-K27] Approved [536779], [540887]
Therapeutic Class
Antiulcer Agents
Company
AstraZeneca
Structure
Download
2D MOL

3D MOL

Formula
C17H19N3O3S
InChI
InChI=1S/C17H19N3O3S/c1-10-8-18-15(11(2)16(10)23-4)9-24(21)17-19-13-6-5-12(22-3)7-14(13)20-17/h5-8H,9H2,1-4H3,(H,19,20)/t24-/m0/s1
InChIKey
SUBDBMMJDZJVOS-DEOSSOPVSA-N
CAS Number
CAS 161796-78-7
PubChem Compound ID
PubChem Substance ID
ChEBI ID
ChEBI:50275
SuperDrug ATC ID
A02BC05
SuperDrug CAS ID
cas=161973100
Target and Pathway
Target(s) H+ K+ ATPase Target Info Modulator [556264]
References
Ref 536779Esomeprazole: a review of its use in the management of gastric acid-related diseases in adults. Drugs. 2008;68(11):1571-607.
Ref 540887(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5488).
Ref 556264Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.

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