TTD | Drug: D0C8SX

Drug General Information
Drug ID	D0C8SX
Former ID	DIB020596
Drug Name	OG-L002
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[542046]
Structure		Download 2D MOL
Formula	C15H15NO
InChI	InChI=1S/C15H15NO/c16-15-9-14(15)11-6-4-10(5-7-11)12-2-1-3-13(17)8-12/h1-8,14-15,17H,9,16H2/t14-,15+/m1/s1
InChIKey	DSOJSZXQRJGBCW-CABCVRRESA-N
PubChem Compound ID	56639570
PubChem Substance ID	134415629, 134431064, 169548929, 178103602, 226088105, 232521606, 252450327, 252472815
Target and Pathway
Target(s)	Lysine specific histone demethylase 1	Target Info	Inhibitor	[532221]
Pathway Interaction Database	Notch signaling pathway
	Coregulation of Androgen receptor activity
	Notch-mediated HES/HEY network
Reactome	HDACs deacetylate histones
	Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3
	Factors involved in megakaryocyte development and platelet production
WikiPathways	Factors involved in megakaryocyte development and platelet production
WikiPathways	Androgen receptor signaling pathway
References
Ref 542046	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7023).
Ref 532221	A novel selective LSD1/KDM1A inhibitor epigenetically blocks herpes simplex virus lytic replication and reactivation from latency. MBio. 2013 Feb 5;4(1):e00558-12.

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Drug Information