Drug General Information
Drug ID	D0CX7I
Former ID	DNC006583
Drug Name	4-tert-butyl-N-m-tolylthiazol-2-amine
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[528047]
Structure		Download 2D MOL 3D MOL
Formula	C14H18N2S
Canonical SMILES	CC1=CC(=CC=C1)NC2=NC(=CS2)C(C)(C)C
InChI	1S/C14H18N2S/c1-10-6-5-7-11(8-10)15-13-16-12(9-17-13)14(2,3)4/h5-9H,1-4H3,(H,15,16)
InChIKey	JCIZSRYCZWHMQK-UHFFFAOYSA-N
PubChem Compound ID	44411325
Target and Pathway
Target(s)	C-Cchemokine receptor type 4	Target Info	Inhibitor	[528047]
KEGG Pathway	Cytokine-cytokine receptor interaction
	Chemokine signaling pathway
	Viral carcinogenesis
PANTHER Pathway	Inflammation mediated by chemokine and cytokine signaling pathway
Reactome	Chemokine receptors bind chemokines
	G alpha (i) signalling events
WikiPathways	GPCRs, Class A Rhodopsin-like
	Peptide GPCRs
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 528047	Bioorg Med Chem Lett. 2006 May 15;16(10):2800-3. Epub 2006 Feb 23.Optimization of 2-aminothiazole derivatives as CCR4 antagonists.
Ref 528047	Bioorg Med Chem Lett. 2006 May 15;16(10):2800-3. Epub 2006 Feb 23.Optimization of 2-aminothiazole derivatives as CCR4 antagonists.

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