Drug Information

Drug General Information
Drug ID
D01XNB
Former ID
DAP000180
Drug Name
Omeprazole
Synonyms
AULCER; Antra; Audazol; Axagon; Belmazol; Ceprandal; Danlox; Demeprazol; Desec; Dizprazol; Dudencer; Elgam; Emeproton; Emilok; Epirazole; Erbolin; Esomeprazol; Esomeprazole; Esomperazole; Esopral; Exter; Gasec; Gastrimut; Gastroloc; Gibancer; Indurgan; Inhibitron; Inhipump; Lensor; Logastric; Lomac; Losec; Lucen; Mepral; Miol; Miracid; Mopral; Morecon; Nexium; Nilsec; Nopramin; Nuclosina; OMEP; OMZ; Ocid; Olexin; Olit; Omapren; Omebeta; Omed; Omegast; Omepradex; Omepral; Omeprazol; Omeprazolum; Omeprazon; Omeprazone; Omeprol; Omesek; Omez; Omezol; Omezolan; Omid; Omisec; Omizac; Ompanyt; Ortanol; Osiren; Ozoken; Paprazol; Parizac; Pepticum; Pepticus; Peptilcer; Prazentol; Prazidec; Prazolit; Prilosec; Procelac; Proclor; Prysma; Ramezol; Regulacid; Result; Sanamidol; Secrepina; Ulceral; Ulcesep; Ulcometion; Ulcozol; Ulcsep; Ulsen; Ultop; Ulzol; Victrix; Zefxon; Zegerid; Zepral; Zimor; Zoltum; Antra MUPS; Nexium IV; Omeprazole magnesium; Prilosec OTC; Tedec Ulceral; O0359; Omebeta 20; AGI-010; DM-3458; H 168-68; H 168/68; Losec (TN); Omeprazol [INN-Spanish]; Omeprazole delayed-release; Omeprazolum [INN-Latin]; Prilosec (TN); SAN-15; H-168/68; Omeprazole (JAN/USP/INN); Omeprazole [USAN:INN:BAN:JAN]; Losec, Omesec, Prilosec, Zegerid, Omeprazole; (-)-Omeprazole; 2-(((3,5-Dimethyl-4-methoxy-2-pyridyl)methyl)sulfinyl)-5-methoxy-1H-benzimidazole; 2-({[3,5-dimethyl-4-(methyloxy)pyridin-2-yl]methyl}sulfinyl)-5-(methyloxy)-1H-benzimidazole; 5-Methoxy-2-(((4-methoxy-3,5-dimethyl-2-pyridyl)methyl)sulfinyl)benzimidazole; 5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole; 5-Methoxy-2[(4-methoxy-3,5-dimethyl-2-pyridyl)methylsulfinyl]-1H-benzimidazole; 5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole; 6-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]-1H-benzimidazole
Drug Type
Small molecular drug
Indication Gastroesophageal reflux disease [ICD9: 140-229, 530; ICD10:K21] Approved [467616], [537527]
Therapeutic Class
Antiulcer Agents
Company
AstraZeneca
Structure
Download
2D MOL

3D MOL
Formula
C17H19N3O3S
InChI
InChI=1S/C17H19N3O3S/c1-10-8-18-15(11(2)16(10)23-4)9-24(21)17-19-13-6-5-12(22-3)7-14(13)20-17/h5-8H,9H2,1-4H3,(H,19,20)
InChIKey
SUBDBMMJDZJVOS-UHFFFAOYSA-N
CAS Number
CAS 73590-58-6
PubChem Compound ID
4594
PubChem Substance ID
9532, 640212, 855576, 3281991, 4696242, 5212304, 7847521, 7980199, 8152819, 10321754, 11112840, 11398365, 11466521, 11467641, 11486042, 11528599, 12013167, 14753960, 14875946, 22391484, 24897870, 26751452, 26751453, 26759296, 29223683, 46386973, 46487906, 46509065, 47365309, 47589088, 47589089, 48035237, 48170542, 48414255, 48416351, 49681572, 49698521, 49834935, 50100529, 50103932, 53788700, 56313300, 56313696, 56313928, 56422106, 57322340, 80295314, 81093370, 85174452, 85788870
ChEBI ID
ChEBI:7772
SuperDrug ATC ID
A02BC01
SuperDrug CAS ID
cas=073590586
Target and Pathway
Target(s) H+ K+ ATPase Target Info Modulator [556264]
References
Ref 467616(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4279).
Ref 537527Generic omeprazole delayed-release capsules: in vitro performance evaluations. Drug Dev Ind Pharm. 2009 Aug;35(8):917-21.
Ref 556264Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.

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