Drug General Information
Drug ID	D02BBN
Former ID	DNC014620
Drug Name	4-Amino-3-benzofuran-2-yl-butyric acid
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[533413]
Structure		Download 2D MOL 3D MOL
Formula	C12H13NO3
Canonical SMILES	C1=CC=C2C(=C1)C=C(O2)C(CC(=O)O)CN
InChI	1S/C12H13NO3/c13-7-9(6-12(14)15)11-5-8-3-1-2-4-10(8)16-11/h1-5,9H,6-7,13H2,(H,14,15)
InChIKey	SRLRWPSSQWUHQC-UHFFFAOYSA-N
PubChem Compound ID	129512
Target and Pathway
Target(s)	Gamma-aminobutyric acid B receptor	Target Info	Inhibitor	[533413]
KEGG Pathway	cAMP signaling pathway
	Neuroactive ligand-receptor interaction
	GABAergic synapse
	Estrogen signaling pathway
	Morphine addiction
Reactome	Activation of G protein gated Potassium channels
	G alpha (i) signalling events
	Class C/3 (Metabotropic glutamate/pheromone receptors)
	Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
WikiPathways	GPCRs, Class C Metabotropic glutamate, pheromone
	Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
	Potassium Channels
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 533413	J Med Chem. 1987 Apr;30(4):743-6.Synthesis and pharmacological evaluation of gamma-aminobutyric acid analogues. New ligand for GABAB sites.
Ref 533413	J Med Chem. 1987 Apr;30(4):743-6.Synthesis and pharmacological evaluation of gamma-aminobutyric acid analogues. New ligand for GABAB sites.

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