Drug General Information
Drug ID
D0Z2CM
Former ID
DAP001103
Drug Name
Lutropin alfa
Synonyms
Luveris; Luveris (TN); Lutropin alfa (USAN/INN)
Indication Female infertility [ICD9: 628; ICD10:N97.0] Approved [536361]
Therapeutic Class
Fertility Agents
Formula
C1014H1609N287O294S27
CAS Number
CAS 152923-57-4
PubChem Substance ID
SuperDrug ATC ID
G03GA07
Target and Pathway
Target(s) Lutropin-choriogonadotropic hormone receptor Target Info Binder [536778]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Ovarian steroidogenesis
Prolactin signaling pathway
NetPath Pathway FSH Signaling Pathway
Pathway Interaction Database Arf6 signaling events
PathWhiz Pathway Intracellular Signalling Through LHCGR Receptor and Luteinizing Hormone/Choriogonadotropin
Reactome Hormone ligand-binding receptors
G alpha (s) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Ovarian Infertility Genes
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 536361Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. Epub 2007 Feb 20.
Ref 536778Lutropin alfa. Drugs. 2008;68(11):1529-40.

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