Drug Information

Drug General Information
Drug ID
D02BCM
Former ID
DNC004905
Drug Name
2-Furan-2-yl-3-phenethyl-3H-quinazolin-4-one
Drug Type
Small molecular drug
Indication Discovery agent Investigative [527540]
Structure
Download
2D MOL

3D MOL
Formula
C20H16N2O2
Canonical SMILES
C1=CC=C(C=C1)CCN2C(=NC3=CC=CC=C3C2=O)C4=CC=CO4
InChI
1S/C20H16N2O2/c23-20-16-9-4-5-10-17(16)21-19(18-11-6-14-24-18)22(20)13-12-15-7-2-1-3-8-15/h1-11,14H,12-13H2
InChIKey
ZFIMKOHGGKYLGR-UHFFFAOYSA-N
PubChem Compound ID
683379
Target and Pathway
Target(s) Extracellular calcium-sensing receptor Target Info Inhibitor [527540]
Pathway Interaction Database E-cadherin signaling in keratinocytes
Reactome G alpha (q) signalling events
G alpha (i) signalling events
Class C/3 (Metabotropic glutamate/pheromone receptors)
WikiPathways GPCRs, Class C Metabotropic glutamate, pheromone
Gastrin-CREB signalling pathway via PKC and MAPK
GPCR ligand binding
GPCR downstream signaling
References
Ref 527540Bioorg Med Chem Lett. 2005 May 16;15(10):2537-40.Design, new synthesis, and calcilytic activity of substituted 3H-pyrimidin-4-ones.
Ref 527540Bioorg Med Chem Lett. 2005 May 16;15(10):2537-40.Design, new synthesis, and calcilytic activity of substituted 3H-pyrimidin-4-ones.

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