Drug General Information
Drug ID	D06AJH
Former ID	DNC006577
Drug Name	4-methyl-N-(naphthalen-1-yl)thiazol-2-amine
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[528047]
Structure		Download 2D MOL 3D MOL
Formula	C14H12N2S
Canonical SMILES	CC1=CSC(=N1)NC2=CC=CC3=CC=CC=C32
InChI	1S/C14H12N2S/c1-10-9-17-14(15-10)16-13-8-4-6-11-5-2-3-7-12(11)13/h2-9H,1H3,(H,15,16)
InChIKey	QNKLFDFMOINNIW-UHFFFAOYSA-N
PubChem Compound ID	692856
Target and Pathway
Target(s)	C-Cchemokine receptor type 4	Target Info	Inhibitor	[528047]
KEGG Pathway	Cytokine-cytokine receptor interaction
	Chemokine signaling pathway
	Viral carcinogenesis
PANTHER Pathway	Inflammation mediated by chemokine and cytokine signaling pathway
Reactome	Chemokine receptors bind chemokines
	G alpha (i) signalling events
WikiPathways	GPCRs, Class A Rhodopsin-like
	Peptide GPCRs
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 528047	Bioorg Med Chem Lett. 2006 May 15;16(10):2800-3. Epub 2006 Feb 23.Optimization of 2-aminothiazole derivatives as CCR4 antagonists.
Ref 528047	Bioorg Med Chem Lett. 2006 May 15;16(10):2800-3. Epub 2006 Feb 23.Optimization of 2-aminothiazole derivatives as CCR4 antagonists.

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