TTD | Drug: D0F1DY

Drug General Information
Drug ID	D0F1DY
Former ID	DCL000418
Drug Name	Albiglutide
Indication	Type 2 diabetes [ICD9: 250; ICD10:E11]		Approved	[533123], [542408]
Company	GSK
Structure		Download 2D MOL
CAS Number	CAS 782500-75-8
Target and Pathway
Target(s)	Glucagon-like peptide 1 receptor	Target Info	Modulator	[533123]
KEGG Pathway	cAMP signaling pathway
	Neuroactive ligand-receptor interaction
	Insulin secretion
Reactome	Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
	G alpha (s) signalling events
	Glucagon-type ligand receptors
WikiPathways	GPCRs, Class B Secretin-like
	Integration of energy metabolism
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 533123	2014 FDA drug approvals. Nat Rev Drug Discov. 2015 Feb;14(2):77-81.
Ref 542408	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7386).
Ref 533123	2014 FDA drug approvals. Nat Rev Drug Discov. 2015 Feb;14(2):77-81.

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Drug Information