Drug General Information
Drug ID	D0E2QN
Former ID	DIB000873
Drug Name	AZD-1678
Synonyms	CCR4 antagonist (asthma), AstraZeneca
Indication	Asthma [ICD10:J45]		Preclinical	[548958]
Company	AstraZeneca plc
Structure		Download 2D MOL 3D MOL
Canonical SMILES	c1(c(c(ccc1)Cl)Cl)S(=O)(=O)Nc1c(nc(cn1)F)OC
Target and Pathway
Target(s)	C-Cchemokine receptor type 4	Target Info	Antagonist	[548959]
KEGG Pathway	Cytokine-cytokine receptor interaction
	Chemokine signaling pathway
	Viral carcinogenesis
PANTHER Pathway	Inflammation mediated by chemokine and cytokine signaling pathway
Reactome	Chemokine receptors bind chemokines
	G alpha (i) signalling events
WikiPathways	GPCRs, Class A Rhodopsin-like
	Peptide GPCRs
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 548958	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800030818)
Ref 548959	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800030818)

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