Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D00PYP
|
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| Former ID |
DCL000175
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| Drug Name |
NBI-37582
|
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| Drug Type |
Small molecular drug
|
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| Indication | Anxiety disorder; Depression [ICD9: 300, 311; ICD10:F30-F39, F40-F42] | Terminated | [527521] | ||
| Company |
Neurocrine Biosci
|
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| Structure |
|
Download2D MOL |
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| Formula |
C31H33Cl2F3N8O8S2
|
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| Canonical SMILES |
CN1CCN(CC1)C2=C(C=C3C(=C2F)N(C=C(C3=O)C(=O)OCC4=C(N5C(C<br />(C5=O)NC(=O)C(=NOC)C6=CSC(=N6)N)SC4)C(=O)O)CCF)F.Cl.Cl
|
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| InChI |
1S/C31H31F3N8O8S2.2ClH/c1-39-5-7-40(8-6-39)24-17(33)9-15-23(19(24)34)41(4-3-32)10-16(25(15)43)30(48)50-11-14-12-51-28-21(27(45)42(28)22(14)29(46)47)37-26(44)20(38-49-2)18-13-52-31(35)36-18;;/h9-10,13,21,28H,3-8,11-12H2,1-2H3,(H2,35,36)(H,37,44)(H,46,47);2*1H/b38-20-;;/t21-,28-;;/m1../s1
|
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| InChIKey |
DSGXXSRGPIYUHF-ZVOUVGCISA-N
|
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| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| Target and Pathway | |||||
| Target(s) | Corticotropin releasing factor receptor 1 | Target Info | Antagonist | [550543] | |
| NetPath Pathway | TNFalpha Signaling Pathway | ||||
| PANTHER Pathway | Cortocotropin releasing factor receptor signaling pathway | ||||
| References | |||||
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