Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0Z4NX
|
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| Former ID |
DIB016927
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| Drug Name |
FR-171113
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| Drug Type |
Small molecular drug
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| Indication | Thrombosis [ICD9: 437.6, 453, 671.5, 671.9; ICD10:I80-I82] | Terminated | [546808] | ||
| Company |
Fujisawa Pharmaceutical Corp
|
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| Structure |
|
Download2D MOL |
|||
| Formula |
C19H11Cl3N2O4S
|
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| Canonical SMILES |
c\1(=C/C(=O)c2cc(c(cc2)Cl)Cl)/n(c(=O)/c(=C\C(=O)OC)/s1)<br />c1ccc(cc1)Cl
|
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| CAS Number |
CAS 173904-50-2
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Thrombin receptor | Target Info | Modulator | [525659] | |
| NetPath Pathway | TGF_beta_Receptor Signaling Pathway | ||||
| TCR Signaling Pathway | |||||
| PANTHER Pathway | Angiogenesis | ||||
| Blood coagulation | |||||
| Pathway Interaction Database | PAR1-mediated thrombin signaling events | ||||
| WikiPathways | Complement and Coagulation Cascades | ||||
| Regulation of Actin Cytoskeleton | |||||
| GPCRs, Class A Rhodopsin-like | |||||
| IL1 and megakaryotyces in obesity | |||||
| Apoptosis-related network due to altered Notch3 in ovarian cancer | |||||
| Hematopoietic Stem Cell Differentiation | |||||
| Gastrin-CREB signalling pathway via PKC and MAPK | |||||
| Thrombin signalling through proteinase activated receptors (PARs) | |||||
| GPCR ligand binding | |||||
| GPCR downstream signaling | |||||
| GPCRs, Other | |||||
| References | |||||
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