Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D08ELM
|
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| Former ID |
DIB002042
|
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| Drug Name |
RWJ-58259
|
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| Drug Type |
Small molecular drug
|
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| Indication | Restenosis [ICD10:I51.89] | Terminated | [526902] | ||
| Company |
RW Johnson Pharmaceutical Research Institute
|
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| Structure |
|
Download2D MOL |
|||
| Formula |
C40H42Cl2F2N8O3
|
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| Canonical SMILES |
n1(nc(c2c1cc(NC(=O)N[C@H](C(=O)N[C@H](C(=O)NCc1ccccc1)C<br />CN)Cc1cc(c(cc1)F)F)cc2)CN1CCCC1)Cc1c(Cl)cccc1Cl
|
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| CAS Number |
CAS 315203-31-7
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Thrombin receptor | Target Info | Modulator | [526902] | |
| NetPath Pathway | TGF_beta_Receptor Signaling Pathway | ||||
| TCR Signaling Pathway | |||||
| PANTHER Pathway | Angiogenesis | ||||
| Blood coagulation | |||||
| Pathway Interaction Database | PAR1-mediated thrombin signaling events | ||||
| WikiPathways | Complement and Coagulation Cascades | ||||
| Regulation of Actin Cytoskeleton | |||||
| GPCRs, Class A Rhodopsin-like | |||||
| IL1 and megakaryotyces in obesity | |||||
| Apoptosis-related network due to altered Notch3 in ovarian cancer | |||||
| Hematopoietic Stem Cell Differentiation | |||||
| Gastrin-CREB signalling pathway via PKC and MAPK | |||||
| Thrombin signalling through proteinase activated receptors (PARs) | |||||
| GPCR ligand binding | |||||
| GPCR downstream signaling | |||||
| GPCRs, Other | |||||
| References | |||||
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