Drug Information

Drug General Information
Drug ID
D05BCU
Former ID
DIB011181
Drug Name
RQ-00000004
Synonyms
PF-03716556; RQ-00000774; RQ-4; Acid pump inhibitor (GERD), Pfizer; Acid pump inhibitor (GERD), RaQualia;Acid pump inhibitor (gastroesophageal reflux), Pfizer; Acid pump inhibitor (gastroesophageal reflux), RaQualia
Indication Gastroesophageal reflux disease [ICD9: 140-229, 530; ICD10:K21] Phase 3 [549204]
Company
Pfizer Inc
Structure
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2D MOL

3D MOL
Canonical SMILES
c1(cc(c2n(c1)cc(n2)C)N[C@@H]1CCOc2c1c(ccc2)C)C(=O)N(CCO<br />)C
Target and Pathway
Target(s) H+ K+ ATPase Target Info Modulator [529788]
References
Ref 549204Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800033657)
Ref 529788N-(2-hydroxyethyl)-N,2-dimethyl-8-{[(4R)-5-methyl-3,4-dihydro-2H-chromen-4-yl]amino}imidazo[1,2-a]pyridine-6-carboxamide (PF-03716556), a novel, potent, and selective acid pump antagonist for the treatment of gastroesophageal reflux disease. J Pharmacol Exp Ther. 2009 Feb;328(2):671-9.

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