Drug Information

Drug General Information
Drug ID
D00UOQ
Former ID
DIB010530
Drug Name
PAT-SC1
Synonyms
SC-1; Adjuvant therapy (gastric cancer), University of Wurzburg; SC-1 (gastric cancer), CAT; SC-1 (gastric cancer), Debiopharm; SC-1 (gastric cancer), Patrys; SC-1 (stomach cancer), OncoMab
Drug Type
Antibody
Indication Gastric cancer [ICD9: 151; ICD10:C16] Phase 1/2 [547138]
Company
Universitat Wurzburg
Target and Pathway
Target(s) CD55 Target Info [532641]
KEGG Pathway Complement and coagulation cascades
Hematopoietic cell lineage
Viral myocarditis
NetPath Pathway IL5 Signaling Pathway
IL2 Signaling Pathway
FSH Signaling Pathway
TGF_beta_Receptor Signaling Pathway
Reactome Class B/2 (Secretin family receptors)
Regulation of Complement cascade
WikiPathways Complement and Coagulation Cascades
Complement Activation, Classical Pathway
Human Complement System
GPCR ligand binding
Complement cascade
References
Ref 547138Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800013314)
Ref 532641Ten-year follow-up of a prospective trial for the targeted therapy of gastric cancer with the human monoclonal antibody PAT-SC1. Oncol Rep. 2014 Mar;31(3):1059-66.

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