Drug Information

Drug General Information
Drug ID
D0A3FZ
Former ID
DNCL002782
Drug Name
Rilimogene galvacirepvec
Synonyms
Prostvac (TN)
Indication Prostate cancer [ICD9: 185; ICD10:C61] Phase 3 [530657]
Company
BM ImmunoTherapeutics
Target and Pathway
Target(s) Prostate specific antigen Target Info Modulator [530657]
KEGG Pathway Pathways in cancer
Prostate cancer
Pathway Interaction Database Coregulation of Androgen receptor activity
Regulation of Androgen receptor activity
FOXA1 transcription factor network
Reactome Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3
WikiPathways Prostate Cancer
Androgen receptor signaling pathway
References
Ref 530657Overall survival analysis of a phase II randomized controlled trial of a Poxviral-based PSA-targeted immunotherapy in metastatic castration-resistant prostate cancer. J Clin Oncol. 2010 Mar 1;28(7):1099-105.
Ref 530657Overall survival analysis of a phase II randomized controlled trial of a Poxviral-based PSA-targeted immunotherapy in metastatic castration-resistant prostate cancer. J Clin Oncol. 2010 Mar 1;28(7):1099-105.

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