Drug Information

Drug General Information
Drug ID
D0K7SX
Former ID
DIB013169
Drug Name
Avelumab
Drug Type
Antibody
Indication Merkel cell carcinoma [ICD10:C4A] Approved [889446]
Cancer [ICD9: 140-229; ICD10:C00-C96] Phase 3 [525127]
Company
Emd Serono
Target and Pathway
Target(s) Programmed cell deathe?Y? ligand 1 (PD-L1) Target Info [533256]
KEGG Pathway Cell adhesion molecules (CAMs)
Reactome PD-1 signaling
WikiPathways Costimulation by the CD28 family
References
Ref 525127ClinicalTrials.gov (NCT02395172) Avelumab in Non-Small Cell Lung Cancer (JAVELIN Lung 200). U.S. National Institutes of Health.
Ref 889446Drugs@FDA (Edaravone)
Ref 533256Antibody-Dependent Cellular Cytotoxicity Activity of a Novel Anti-PD-L1 Antibody Avelumab (MSB0010718C) on Human Tumor Cells. Cancer Immunol Res. 2015 Oct;3(10):1148-57.

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